Medindia
Advertisement

Higher Risk of Wound Complications After Surgery Found in Patients With High Blood Sugar Levels

by Thilaka Ravi on October 2, 2013 at 1:22 PM
Font : A-A+

Higher Risk of Wound Complications After Surgery Found in Patients With High Blood Sugar Levels

A new study among patients undergoing surgery for chronic wounds related to diabetes, finds the risk of wound-related complications is affected by how well the patient's blood sugar levels are controlled before surgery. These findings appear in the October issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons(ASPS).

The risk of serious wound complications is more than three times higher for patients who have high blood glucose before and after surgery, and in those with poor long-term diabetes control, according to the study by ASPS Member Surgeons Drs. Matthew Endara and Christopher Attinger of the Center for Wound Healing at Georgetown University, Washington, DC. The researchers emphasize the need for "tight control" of glucose levels before surgery for diabetic patients at high risk of wound complications.

Advertisement

High Blood Glucose Levels Linked to Higher Risk of Wound Complications The researchers analyzed rates of wound-related complications in 79 patients undergoing surgery for closure of chronic wounds—a common and troublesome complication of diabetes. Blood glucose levels were measured five days before and after surgery. Hemoglobin A1c, a key indicator of long-term diabetes control, was measured an average of two weeks before surgery.

Blood glucose levels and diabetes control were analyzed as risk factors for wound dehiscence (a serious complication in which the surgical incision re-opens), wound infections and need for repeat surgery. Blood glucose levels over 200 were considered to represent elevated blood glucose (hyperglycemia).
Advertisement

The results showed a higher risk of wound complications in patients who had high blood glucose levels either before or after surgery. For example, wound dehiscence occurred in about 44 percent of patients who had high glucose levels before surgery, compared to 19 percent of those without preoperative hyperglycemia.

The risk of wound dehiscence was also higher for patients with high blood glucose levels after surgery and for those with high hemoglobin A1c levels (that is, poor long-term diabetes control). With adjustment for other factors, the risk of wound dehiscence was more than three times higher for patients with hyperglycemia or elevated hemoglobin A1c around the time of surgery.

Need for 'Tight Control' of Glucose Levels during Surgery Patients with wide swings in blood glucose levels—variation of more than 200 points—were about four times more likely to undergo repeat surgery. Otherwise, blood glucose levels and hemoglobin A1c were unrelated to the risk of reoperation or wound infections.

In recent years, tight control of blood glucose levels has been shown to improve a wide array of outcomes in patients with diabetes. For patients with chronic skin ulcers occurring as a complication of diabetes, hyperglycemia has been linked to delayed wound healing and an increased risk of infections. Surprisingly, the new study is one of the first to look at how blood glucose levels affect the risk of complications in patients undergoing surgical treatment for chronic diabetes-related wounds.

"Chronic and perioperative glucose management in high-risk patients undergoing surgical closure of their wounds is significantly associated with outcomes," Dr. Attinger and colleagues write. They note that episodes of high blood glucose can occur around the time of surgery even in many patients with previously good diabetes control.

The results help to make the case for "tighter glycemic control" in diabetic patients undergoing surgery with a high risk of wound complications, Dr. Attinger and co-authors believe. They note that surgeons may need to consult with specialists to manage diabetes control in these "medically complex patients." However, more research will be needed to confirm whether tighter control of blood glucose levels around the time of surgery will actually reduce the rate of wound-related complications.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Gonorrhea
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Thalassemia Diabetes - Essentials Diabetes - Self-Monitoring of Blood Glucose (SMBG) Decoding HbA1c Test for Blood Sugar Hunger Fullness and Weight Control Carbohydrates and Its Role in Obesity Sugar: Time to Look beyond Its Sweetness The Better Flour - Refined Or Whole Wheat Flour! Remedies to Treat Diabetes Naturally Tips for Healthy Fasting During Ramadhan 

Recommended Reading
Type 2 Diabetes
Globalization and changing lifestyles has made diabetes very common in developing countries so much ...
Diabetes
A comprehensive article on diabetes - both Type 1 and Type 2 diabetes, including : causes, signs, .....
Diabetes - Foot Care
Valuable information on diabetic foot care, treatment and prevention....
Remedies to Treat Diabetes Naturally
An article about the natural remedies available at home to treat diabetes effectively and ......
Carbohydrates and Its Role in Obesity
Obesity is a global epidemic with majority of the world’s population in developed countries being ov...
Decoding HbA1c Test for Blood Sugar
The HbA1c assay is the gold-standard measurement of chronic glycemia and measures the amount of gluc...
Diabetes - Essentials
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels a...
Diabetes - Self-Monitoring of Blood Glucose (SMBG)
Self-Monitoring Of Blood Glucose (SMBG) is one of the greatest advancements in the management of Di...
Hunger Fullness and Weight Control
An erratic way of eating or any metabolic disturbance in the hunger fullness signals is one of the m...
Sugar: Time to Look beyond Its Sweetness
Sugar is known to be the dietary cause for increased risk of several chronic ailments such as diabet...
Thalassemia
Thalassemia is an inherited blood disorder passed on through parental genes causing the body to prod...
The Better Flour - Refined Or Whole Wheat Flour!
Whole wheat flour is rapidly gaining exposure for its rich nutritional value and being considered he...
Tips for Healthy Fasting During Ramadhan
Ramadhan calls for a change in your food habits, and to help you glide through it easily, here we’ve...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use