Researchers at Center for Medical Ethics and Health Policy at Baylor College of Medicine have come out with a framework for the new American College of Medical Genetics and Genomics (ACMG) recommendations on reporting incidental findings in clinical exome and genome sequencing, according to a report published in Science Express.
In March 2013, the ACMG recommended that all laboratories conducting clinical sequencing seek and report pathogenic and expected pathogenic mutations for a short list of carefully chosen genes and conditions.
Genetic Testing of Diseases
Genetic testing helps to confirm a genetic condition in an individual and involves q complex laboratory techniques
Advertisement
In this paper, Dr. Amy McGuire, director of the Center for Ethics and Health Policy at BCM and a lead author on the paper, and colleagues from BCM, Harvard Medical School, The University of California San Francisco, The National Human Genome Research Institute, The University of Alberta in Edmonton, Canada and the Genetic Alliance explain why they believe the ACMG position that laboratories have an obligation to report clinically beneficial incidental findings is ethically justified and compatible with respect for patient autonomy.
Source: Eurekalert
Epigenetics
In the recent years 'epigenetics' represents inheritable changes in gene expression that do not include DNA alterations.
Advertisement
 Birth Defect - GeneticAchondroplasia is a genetic disorder which is one of the leading causes of dwarfism | Advertisement
|
Advertisement
Recommended Readings
Latest Genetics & Stem Cells News
Scientists have developed the first humanized mouse model for a rare hereditary condition.
A recent study discovered that the placenta, rather than only the brain, is crucial in determining the genetic risk of schizophrenia.
FOXI3 gene was found to be involved in Goldenhar syndrome, one form of developmental disorder, revealed research.
Contrary to previous beliefs, genes may not be fixed and can be influenced by environmental factors and lifestyle choices, according to modern scientific research.
Gene therapy successfully tested on dogs with inherited eye disease is now poised for clinical use in humans.