A topical application of an extract of broccoli sprouts may help protect people from the damaging effects of ultraviolet (UV) radiation say researchers from Johns Hopkins.
After positive trials in mice, the researchers conducted experiments on six healthy human volunteers.
Prevention of Ultraviolet Radiation
Protective measures to be taken to avoid the effects of overexposure to sun
Advertisement
Each volunteer was exposed to a pulse of UV radiation on small patches of their skin (less than 1 inch in diameter) that were either treated or untreated with different doses of broccoli extract.
The researchers found that the degree of skin redness (erythema) caused by UV rays, which is an accurate index of the inflammation and cell damage caused by UV radiation, is markedly reduced when treated with the extract.
![Super Foods - Broccoli sprouts]( "Super Foods - Broccoli sprouts")
Encyclopedia section of medindia explains in brief about the beneficial aspects of consuming broccoli sprouts, which helps in preventing and controlling cancer
At the highest doses, UV-induced redness and inflammation were reduced by an average of 37 percent. The extracts were protective even when applied three days prior to UV exposure. The protection did vary considerably among the subjects, ranging from 8 percent to 78 percent.
Lead researcher Paul Talalay, M.D., professor of pharmacology, more importantly revealed that the extract is not a sunscreen. Sunscreens work by absorbing UV light and preventing its entry into the skin. This extract on the other hand, works inside cells by boosting the production of a network of protective enzymes that defend cells against many aspects of UV damage.
As a result, the effects are long lasting. The protection lasts for several days, even after the extract is no longer present on or in the skin. Talalay says: "Treatment with this broccoli sprout extract might be another protective measure that alleviates the skin damage caused by UV radiation and thereby decreases our long-term risk of developing cancer."
The protective chemical agent in the broccoli sprout extracts is sulforaphane. It was first identified by Talalay and his colleagues more than 15 years ago and has been shown to prevent tumor development in a number of animals treated with cancer-causing chemicals.
The study appears in this week's issue of the Proceedings of the National Academy of Sciences.
Source: ANI
LIN/C
Super Foods - Broccoli sprouts
Encyclopedia section of medindia explains in brief about the beneficial aspects of consuming broccoli sprouts, which helps in preventing and controlling cancer
Advertisement
At the highest doses, UV-induced redness and inflammation were reduced by an average of 37 percent. The extracts were protective even when applied three days prior to UV exposure. The protection did vary considerably among the subjects, ranging from 8 percent to 78 percent.
Lead researcher Paul Talalay, M.D., professor of pharmacology, more importantly revealed that the extract is not a sunscreen. Sunscreens work by absorbing UV light and preventing its entry into the skin. This extract on the other hand, works inside cells by boosting the production of a network of protective enzymes that defend cells against many aspects of UV damage.
As a result, the effects are long lasting. The protection lasts for several days, even after the extract is no longer present on or in the skin. Talalay says: "Treatment with this broccoli sprout extract might be another protective measure that alleviates the skin damage caused by UV radiation and thereby decreases our long-term risk of developing cancer."
The protective chemical agent in the broccoli sprout extracts is sulforaphane. It was first identified by Talalay and his colleagues more than 15 years ago and has been shown to prevent tumor development in a number of animals treated with cancer-causing chemicals.
The study appears in this week's issue of the Proceedings of the National Academy of Sciences.
Source: ANI
LIN/C
Advertisement
Advertisement
|
Advertisement
Recommended Reading
Latest Cancer News
Comprehending the association between the gut microbiome and polyp growth sheds insights into potential screenings and treatments.
The first large-scale, collaborative, open analysis of genomic data provides a cloud-based resource for researchers looking for more comprehensive data on pediatric brain tumors.
The mission of Axiom Space incorporated numerous experiments focusing on human stem cell aging, inflammation, and cancer within the laboratory situated in the low Earth orbit.
Providing a sustained supply of hydrogen sulfide to cancer cells, could be a remodeling strategy to improve photothermal therapy efficacy while minimizing side effects.
Colon cancer's hidden link revealed in microbiome study.