Exercise Program Improves Symptoms in Women With Fibromyalgia

by Medindia Content Team on November 13, 2007 at 8:13 PM

An exercise program that incorporates walking, strength training and stretching may improve daily function and alleviate symptoms in women with fibromyalgia, according to a report, according to an issue in the JAMA/Archives journals. These benefits appear to be enhanced when exercise is combined with education about managing the disease.

Fibromyalgia affects approximately 3.4 percent of women and 0.5 percent of men in the United States, according to background information in the article. Patients with fibromyalgia experience chronic pain throughout their bodies for at least three months, along with specific sites of tenderness. Causes and mechanisms are poorly understood. "Even with the recent approval of pregabalin by the Food and Drug Administration to treat fibromyalgia symptoms, pharmacotherapy is often insufficient to resolve persistent symptoms or improve functional limitations and quality of life," the authors write.

Neuron Mismatch Could Cause Pain in Fibromyalgia Patients

Patients with fibromyalgia often suffer from unexplained pain and scientists suggest that it could be due to a mismatch between sensory and motor systems.

Daniel S. Rooks, Sc.D., from Brigham & Women's Hospital and Harvard Medical School, Boston, and now with Novartis Institutes for Biomedical Research, Inc., Cambridge, Mass., and colleagues recruited 207 women taking medication for fibromyalgia between 2002 and 2004. For 16 weeks, the women were randomly assigned to four groups: 51 performed aerobic and flexibility exercises only; 51 added in strength training; 50 received a self-help course on managing fibromyalgia; and 55 participated in all the exercises and the education course. The exercise groups met twice weekly, gradually increasing the length and intensity of their workouts, with instructions to perform a third day of exercise on their own.

A total of 135 women completed the study and underwent a six-month follow-up assessment. As measured by two self-assessment questionnaires and one performance test, women who participated in all forms of exercise improved their physical function, an effect that was larger in the combined education and exercise group. "Social function, mental health, fatigue, depression and self-efficacy also improved," the authors write. "The beneficial effect on physical function of exercise alone and in combination with education persisted at six months."

Research Explains Why Painkillers are Ineffective on Fibromyalgia

Patients with fibromyalgia were found to have reduced binding ability of a type of receptor in the brain that is the target of opioid painkiller drugs such as morphine.

"The present study suggests that progressive walking, simple strength training movements and stretching activities are effective at improving physical, emotional and social function, key symptoms and self-efficacy in women with fibromyalgia who are being actively treated with medication," the authors write. "Furthermore, the benefits of exercise are enhanced when combined with targeted self-management education, and improvements in physical function continue for six months after completion of the intervention. Our findings suggest the need for inclusion of appropriate exercise and patient education in the treatment of individuals with fibromyalgia."

Source: Eurekalert
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