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Excess Fat in Stomach may Lead to Cancer

by Jayashree on September 4, 2007 at 5:35 PM
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Excess Fat in Stomach may Lead to Cancer

A new study has given people another good reason to lose all that extra weight by finding that fat in the stomach may cause vitamin C to promote the formation of certain cancer causing chemicals rather than preventing it.

As a part of their study the researchers set out to find the impact of fat and lipid) and vitamin C (ascorbic acid) on nitrite chemistry in the upper (proximal) stomach.

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The upper stomach is especially vulnerable to pre-cancerous changes and tumour growth.

The researchers replicated the chemical conditions of the proximal stomach and measured the formation of nitrosamines, oxygen, and nitric oxide.
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Nitrosamines are cancer causing compounds formed in acidic conditions, such as those afforded by stomach acid.

In most circumstances, vitamin C inhibits the formation of nitrosamines by converting nitrite to nitric oxide, reports the BMJ.

However, the study showed that adding ten percent fat had vitamin C boosting the production of nitrosamines between 8 and 140-fold.

The findings may be relevant to the recent observations that vitamin C supplements fail to reduce cancer risk.

The study is published ahead of print in the journal Gut.

Source: ANI
JAY/C
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