About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Even One Sleepless Night can Trigger Inflammation

by Rajashri on September 4, 2008 at 3:38 PM
Font : A-A+

 Even One Sleepless Night can Trigger Inflammation

A new study has found that just one sleepless night can trigger the key cellular pathway that produces tissue-damaging inflammation.

During the study, the researchers measured the levels of nuclear factor (NF)-?B, a transcription factor that serves a vital role in the body's inflammatory signalling, in adults.

Advertisement

These measurements were repeatedly assessed, including in the morning after baseline (or normal) sleep, after partial sleep deprivation (where the volunteers were awake from 11 pm to 3:00 am), and after recovery sleep

The assessment showed that in the morning after sleep loss, activation of NF-?B signalling was significantly greater than after baseline or recovery sleep, although they found this increase in inflammatory response in only the female subjects.
Advertisement

The researchers said that the new findings suggest a good night's sleep can ease the risk of both heart disease and autoimmune disorders such as rheumatoid arthritis.

"The closer that we look at sleep, the more that we learn about the benefits of sleeping. In this case, Irwin and colleagues provide evidence that sleep deprivation is associated with enhancement of pro-inflammatory processes in the body," said John H. Krystal, M.D., Editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System.

"Our findings suggest even modest sleep loss may play a role in common disorders that affect sweeping segments of the population." In other words, sleep is vitally important to maintaining a healthy body," said Dr. Irwin, lead author and director of the Cousins Center for Psychoneuroimmunology at the Semel Institute.

"These findings provide a potential mechanistic avenue through which addressing sleep disturbance might improve health," Krystal added.

A report appears in the September 15th issue of Biological Psychiatry.

Source: ANI
RAS/N
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Menstrual Disorders
Coffee May Help You Fight Endometrial Cancer
Fermented Skin Care
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Insomnia Inflammation 

Recommended Reading
Sleep Disorder
Sleep disorders can either be having difficulty in getting sleep or dozing off at inappropriate ......
What are the Causes of Snoring?
Nasal passageway abnormalities, age, weight gain, sleeping posture, and the use of medications and ....
Ageing and Sleep
Sleep is a barometer of good health in the elderly. Sleep problems in the elderly are controlled by ...
Obstructive Sleep Apnea - Animation
Obstructive sleep apnea occurs when the tissue in the back of the throat collapses completely ......
Inflammation
Inflammation is the response of living tissue to injury due to a variety of causes that call upon ho...
Insomnia
Difficulty in initiating and maintaining sleep is known as insomnia. It is a symptom that occurs due...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)