At some point in their lives, millions of women will develop breast cancer.
While many women will completely recover from this cancer, others will not respond to treatment, and predicting which women will not respond to treatment is currently difficult. Breast cancer cells divide rapidly, and treatments that can restrict their growth are of great interest.
In a June 24th study in the Journal of Clinical Investigation, Rong Li and colleagues at the University of Texas determined that activation of the estrogen receptor β (ERβ) limits tumor cell growth. Cancer cells with activated ERβ did not grow well in culture or in mouse models.