About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Environment and Gene Affect Severity of Suicide Attempt

by Chrisy Ngilneii on January 3, 2018 at 12:32 PM
Font : A-A+

Environment and Gene Affect Severity of Suicide Attempt

Genetic changes in the CRH gene, which affects the regulation of the body's stress system, to suicide risk and psychiatric illness. A study of epigenetic changes in the body's hormone-based stress system has shown that stress-related changes in the CRH gene are linked to both serious suicide attempts in adults and psychiatric illness in adolescents.

Previous studies have indicated an overactive stress system in individuals with increased suicide risk. In the current study, researchers report that epigenetic changes in the CRH gene, which are linked to serious suicide attempts in adults, could also be found in adolescents with a high risk of psychiatric illness.

Advertisement


Recently published research output shows that serious suicide attempts lead to a heavily reduced lifespan with an increased suicide risk and risk of mortality from natural causes particularly in adolescents. In the last ten years, it has become twice as common for Swedish adolescents between the ages of 10 and 17 to suffer from psychiatric illness. An alarming increase also in young adults can be seen. This according to a recently published report from the Swedish National Board of Health and Welfare.

In the study, researchers examined 88 individuals who had attempted suicide. The participants were divided into high and low-risk groups based upon the severity of their suicidal behavior. Through blood samples of the participants, epigenetic markers in the form of DNA methylation in the stress system-related genes were analyzed.
Advertisement

In the next step, the discovered epigenetic changes in the CRH gene were studied in blood samples from two other cohort studies including 129 and 93 adolescents respectively in the age span of 14 to 17. The adolescents were divided into high and low-risk groups based upon assessments of their psychiatric symptoms. The results show that epigenetic changes in the CRH gene were more prevalent in the group of adolescents with an increased risk of psychiatric illness.

"Since psychiatric illness is a serious and growing public health problem, it's important that we take early signs of psychiatric illness and suicidal behavior into consideration in suicide prevention," says Jussi Jokinen, professor in psychiatry at Umea University who led the current study.

"Our environment affects our genetic expression, which is usually referred to as epigenetic change. Even if we aren't able to draw distinct parallels between the findings in these cohort studies, our results still point towards the importance of an optimal regulation of the stress system for psychiatric illness."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Turmeric: Magic Ingredient to Keep you Healthy in Winter
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Adolescence Depression DNA Finger Printing Suicide Stress Relief Through Alternative Medicine Bereavement Quiz on Depression Weaver Syndrome 

Recommended Reading
Suicide
Suicide is an act of ending one's own life and it usually results from emotional isolations and ......
Depression Symptom Evaluation
Depression occurs due to alterations in the levels of neurotransmitters in the brain. ...
Adolescent Depression
Adolescent depression is an ailment that occurs during the teenage characterized by persistent ......
Mental Health - Neurosis vs Psychosis
Mental well-being is a concern and abnormal coping of emotions can lead to neurosis or psychosis. .....
Bereavement
Bereavement refers to grief, pain and sadness following the loss of a loved one, especially during t...
DNA Finger Printing
DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, id...
Weaver Syndrome
Weaver syndrome is a genetic disorder in which children show accelerated bone growth, advanced bone ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use