The connectivity of an individual's brain and their intelligence can now be determined by a newly developed brain mapping technique which is relatively simpler too, reveals researchers at the Cambridge University.
In recent years, there has been a concerted effort among scientists to map the connections in the brain, the so-called 'connectome' and to understand how this relates to human behaviors, such as intelligence and mental health disorders.
Ultra-high Field 7 Tesla fMRI Allows Brain Mapping of Artificial Limbs
The brain re-maps motor and sensory pathways following targeted motor and sensory re-innervation (TMSR), says study.
Advertisement
‘The connectivity in the Morphometric Similarity Networks in the brain region is linked to higher order functions like problem solving ability, language and intelligence.’
Tweet it Now
Now, in research published in the journal Neuron, an international team led by scientists at the University of Cambridge and the National Institutes of Health (NIH), USA, has shown that it is possible to build up a map of the connectome by analyzing conventional brain scans taken using a magnetic resonance imaging (MRI) scanner.
The team compared the brains of 296 typically-developing adolescent volunteers. Their results were then validated in a cohort of a further 124 volunteers. The team used a conventional 3T MRI scanner, where 3T represents the strength of the magnetic field; however, Cambridge has recently installed a much more powerful Siemens 7T Terra MRI scanner, which should allow this technique to give an even more precise mapping of the human brain.
![Brain Mapping Of Nicotine Addiction Helps In Better Understanding Of The Process]( "Brain Mapping Of Nicotine Addiction Helps In Better Understanding Of The Process")
3-dimensional structure of the nicotine receptor will help understand how nicotine addiction occurs in the brain and will help discover new treatments.
A typical MRI scan will provide a single image of the brain, from which it is possible to calculate multiple structural features of the brain. This means that every region of the brain can be described using as many as ten different characteristics.
The researchers showed that if two regions have similar profiles, then they are described as having 'morphometric similarity' and it can be assumed that they are a connected network. They verified this assumption using publicly-available MRI data on a cohort of 31 juvenile rhesus macaque monkeys to compare to 'gold-standard' connectivity estimates in that species.
Using these morphometric similarity networks (MSNs), the researchers were able to build up a map showing how well connected the 'hubs', the major connection points between different regions of the brain network were.
They found a link between the connectivity in the MSNs in brain regions linked to higher order functions, such as problem solving and language and intelligence.
"We saw a clear link between the 'hubbiness' of higher-order brain regions, in other words, how densely connected they were to the rest of the network and an individual's IQ," explains PhD candidate Jakob Seidlitz at the University of Cambridge and NIH. "This makes sense if you think of the hubs as enabling the flow of information around the brain, the stronger the connection, the better the brain is at processing information."
While IQ varied across the participants, the MSNs accounted for around 40% of this variation, it is possible that higher-resolution multi-modal data provided by a 7T scanner may be able to account for an even greater proportion of the individual variation, say the researchers.
"What this doesn't tell us, though, is where exactly this variation comes from," adds Seidlitz. "What makes some brains more connected than others - is it down to their genetics or their educational upbringing, for example? And how do these connections strengthen or weaken across development?"
"This could take us closer to being able to get an idea of intelligence from brain scans, rather than having to rely on IQ tests," says Professor Ed Bullmore, Head of Psychiatry at Cambridge. "Our new mapping technique could also help us understand how the symptoms of mental health disorders such as anxiety and depression or even schizophrenia arise from differences in connectivity within the brain."
Source: Eurekalert
Brain Mapping Of Nicotine Addiction Helps In Better Understanding Of The Process
3-dimensional structure of the nicotine receptor will help understand how nicotine addiction occurs in the brain and will help discover new treatments.
Advertisement
A typical MRI scan will provide a single image of the brain, from which it is possible to calculate multiple structural features of the brain. This means that every region of the brain can be described using as many as ten different characteristics.
The researchers showed that if two regions have similar profiles, then they are described as having 'morphometric similarity' and it can be assumed that they are a connected network. They verified this assumption using publicly-available MRI data on a cohort of 31 juvenile rhesus macaque monkeys to compare to 'gold-standard' connectivity estimates in that species.
Using these morphometric similarity networks (MSNs), the researchers were able to build up a map showing how well connected the 'hubs', the major connection points between different regions of the brain network were.
They found a link between the connectivity in the MSNs in brain regions linked to higher order functions, such as problem solving and language and intelligence.
"We saw a clear link between the 'hubbiness' of higher-order brain regions, in other words, how densely connected they were to the rest of the network and an individual's IQ," explains PhD candidate Jakob Seidlitz at the University of Cambridge and NIH. "This makes sense if you think of the hubs as enabling the flow of information around the brain, the stronger the connection, the better the brain is at processing information."
While IQ varied across the participants, the MSNs accounted for around 40% of this variation, it is possible that higher-resolution multi-modal data provided by a 7T scanner may be able to account for an even greater proportion of the individual variation, say the researchers.
"What this doesn't tell us, though, is where exactly this variation comes from," adds Seidlitz. "What makes some brains more connected than others - is it down to their genetics or their educational upbringing, for example? And how do these connections strengthen or weaken across development?"
"This could take us closer to being able to get an idea of intelligence from brain scans, rather than having to rely on IQ tests," says Professor Ed Bullmore, Head of Psychiatry at Cambridge. "Our new mapping technique could also help us understand how the symptoms of mental health disorders such as anxiety and depression or even schizophrenia arise from differences in connectivity within the brain."
Source: Eurekalert
Spherical Brain Mapping for the Detection of Alzheimer's Disease
Diagnosis, treatment and care of dementia is one of the major concerns in neurology research and associated healthcare programs.
Advertisement
 Brain Mapping Shows Patients With Schizophrenia Have Reduced Imitation AbilityAn impaired ability to imitate may underlie the profound and enduring difficulty with social interactions that characterize schizophrenia. | Advertisement
|
Advertisement
Recommended Reading
Latest Research News
Researchers found that treatments helping to repair nerve damage in neurons in a near-embryonic state might potentially restore sight and movement.
Tobacco smoke contains toxic chemicals which damage lungs, weaken the immune system and cause tuberculosis.
Identifying an unappreciated relationship between brain shape and activity overturns the century-old paradigm emphasizing the importance of complex brain connectivity.
Decoding the eight factors affecting Black adults' life expectancy.
Sobering truth about foot travel in the United States emerges from international statistics, highlighting the prevalence of walking on the Blacksburg campus.