About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Crack in Stomach Ulcer Bacteria Could Lead to New Antibiotics

by VR Sreeraman on October 3, 2009 at 1:36 PM
Font : A-A+

 Crack in Stomach Ulcer Bacteria Could Lead to New Antibiotics

Scientists claim to have identified a crack in the armor of a common microbe that causes stomach ulcers and other diseases.

They have identified a group of substances that block a key chemical pathway that the bacteria need for survival, which could lead to more effective antibiotics to fight these hard-to-treat microbes

Advertisement

Lead researcher Javier Sancho revealed that Helicobacter pylori (H. pylori) bacteria infect the stomach lining and can cause gastritis and ulcers. Treatment with broad-spectrum antibiotics can cure H. pylori infections.

Scientists were already aware that blocking flavodoxin, a key protein that H. pylori needs for survival, could be the key to developing narrow-spectrum antibiotics that specifically target H. pylori.
Advertisement

In the new study, Sancho's team screened 10,000 chemicals for their ability to block flavodoxin and identified four that showed promise.

They then showed that three of the four substances killed H. pylori in cell cultures and did not have any apparent toxic effects in lab animals.

"These new inhibitors constitute promising candidates to develop new specific antibiotics against H. pylori," said the study.

The study will appear in ACS Chemical Biology, a monthly journal.

Source: ANI
SRM
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Organ Donation Week 2022 - 'Take the Pledge to Save Lives'
Test your Knowledge on Heart Transplantation
Test Your Knowledge on Lung Transplantation
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Shigellosis MRSA - The Super Bug Indigestion Zollinger-Ellison Syndrome Food Safety for Health Digestive Tract Ulcers Symptom Evaluation Antibiotics COX - 2 Inhibitors 

Most Popular on Medindia

Blood Pressure Calculator Drug Side Effects Calculator Drug - Food Interactions Post-Nasal Drip Indian Medical Journals Noscaphene (Noscapine) Iron Intake Calculator Find a Doctor Find a Hospital Daily Calorie Requirements
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use