Instead of multiple daily insulin injections, using sensors and insulin pump could bring down average blood sugar levels in diabetics, according to a study.
The study was conducted on 485 participants with inadequately controlled type 1 diabetes, who ranged in ages from seven to 70, and were treated for at least one year, in a randomized, controlled trial.
"Combining the best technologies for insulin delivery and blood sugar monitoring really pays off for diabetes control," says Dr. Bruce Perkins, one of the co-authors of the study, endocrinologist at Toronto General Hospital and Assistant Professor at the University of Toronto.
Research conducted at 30 centres across North America, including Toronto General Hospital, found a significant decrease in average blood sugar levels (or A1c levels, which measure the average blood sugar levels over the past two or three months) from a baseline of 8.3 percent to 7.5 percent in the group using sensors and insulin pumps, compared to 8.3 percent to 8.1 percent in the multiple daily injection group, in one year.
The decrease in A1c levels in both adults and children occurred without an increase in the rate of severe hypoglycemia, or low blood sugar, a general problem among patients who are trying to achieve better control of their blood sugar.
Moreover, the proportion of participants who reached the A1c target of 7% or less was greater in the pump-therapy group than in the injection-therapy group.
The paper is published in the New England Journal of Medicine.