A new study presented at the 2014 American Thoracic Society International Conference suggests that cigarette smoking and male sex are significant risk factors for developing ocular sarcoidosis.
Sarcoidosis is a disease in which inflammation produces tiny lumps of cells (called granulomas) in organs throughout the body, most often in the lungs, but also in the eyes, lymph nodes, or skin. Ocular sarcoidosis, which can lead to blindness, affects 25-50% of sarcoidosis patients.
"Risk factors for ocular sarcoidosis have not been well studied," said lead author Adam Janot, MD, of the Virginia Commonwealth University School of Medicine in Richmond. "Accordingly, we reviewed the cases of 109 patients with biopsy-proven sarcoidosis and identified independent risk factors for developing ocular morbidity."