About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Cancer History Determines Treatment of Heart Attack Patients

by Bidita Debnath on September 23, 2017 at 11:52 PM
Font : A-A+

 Cancer History Determines Treatment of Heart Attack Patients

A heart attack happens when there is a sudden loss of blood flow to a part of your heart muscle. Treatment of heart attack patients depends on their history of cancer.

This is according to research published in European Heart Journal: Acute Cardiovascular Care. The study in more than 35 000 heart attack patients found they were less likely to receive recommended drugs and interventions, and more likely to die in hospital if they had cancer than if they did not.

Advertisement


"It is well known that cancer patients may have an increased risk of cardiovascular disease as a result of their treatment," said senior author Dr Dragana Radovanovic, head of the AMIS Plus Data Centre in Zurich, Switzerland. "However, on the other hand, little is known about the treatment and outcomes of cancer patients who have an acute myocardial infarction."

This study investigated whether acute myocardial infarction patients with a history of cancer received the same guideline recommended treatment and had the same in-hospital outcomes as those without cancer.
Advertisement

The study included 35 249 patients enrolled in the acute myocardial infarction in Switzerland (AMIS Plus) registry between 2002 and mid-2015. Of those, 1 981 (5.6%) had a history of cancer.

Propensity score matching was used to create two groups of 1 981 patients each - one with cancer history and one without - that were matched for age, gender, and cardiovascular risk factors.

The researchers compared the proportions of patients in each group who received specific immediate drug therapies for acute myocardial infarction, and percutaneous coronary intervention (PCI) to open blocked arteries. They also compared the rates of in-hospital complications and death between the two groups.

The researchers found that cancer patients underwent PCI less frequently (odds ratio [OR], 0.76; 95% confidence interval [CI], 0.67-0.88) and received P2Y12 blockers (OR, 0.82; 95% CI 0.71-0.94) and statins (OR, 0.87; 95% CI, 0.76-0.99) less frequently. In-hospital mortality was significantly higher in patients with cancer than those without (10.7% versus 7.6%; OR, 1.45; 95% CI, 1.17-1.81).

Patients with a history of cancer were more likely to have complications while in hospital. They had 44% higher odds of cardiogenic shock, 47% higher chance of bleeding, and 67% greater odds of developing heart failure than those with no history of cancer.

Dr Radovanovic said: "Patients with a history of cancer were less likely to receive evidence-based treatments for myocardial infarction. They were 24% less likely to undergo PCI, 18% less likely to receive P2Y12 antagonists and 13% less likely to receive statins. They had also more complications and were 45% more likely to die while in hospital."

"More research is needed to find out why cancer patients receive suboptimal treatment for myocardial infarction and have poorer outcomes," continued Dr Radovanovic.

"Possible reasons could be the type and stage of cancer, or severe comorbidities. Some cancer patients may have a very limited life expectancy and refuse treatment for myocardial infarction," she added.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Green Mediterranean Diet may Help Repair Age-Related Brain Damages
Cervical Cancer Awareness Month 2022
Ultra-Low-Fat Diet
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Chest Pain Cancer and Homeopathy Cardiac Catheterization Heart Attack Diet Lifestyle and Heart Disease Coronary Artery Bypass Grafting Stress and the Gender Divide Heart Attack Facts Cancer Facts Heart 

Recommended Reading
Beta Blockers Unnecessary After Heart Attack If Other Drugs Followed
Beta blockers may not benefit heart attack survivors compared to ACE inhibitors and statins, ......
First One Hour After Heart Attack Is of Utmost Importance
Shortness of breath is the most common symptom of acute heart failure. From there, the symptoms ......
E-cigarettes Cause Arterial Stiffness and May Up Risk of Heart Attack
People who use E-cigarettes have increased drastically in the past few years. E-cigarettes with ......
Bioactive Molecule may Protect Against Congestive Heart Failure After Heart Attacks
Leukocytes rush to the heart muscle to remove dead cells and begin building scar tissue. Low-grade ...
Cardiac Catheterization
Cardiac catheterization is a radiological procedure for both diagnosis and treatment of heart condit...
Chest Pain
Ask any one who has experienced intense chest pain and they will vouch for the fact that it was the ...
Coronary Artery Bypass Grafting
Coronary artery bypass grafting (CABG) or heart bypass surgery is an open heart surgery to relieve t...
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the lead...
Stress and the Gender Divide
Stress has become entwined in the current lifestyle of a young working couple and has resulted in th...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)