About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Breast Tenderness After Hormone Replacement Therapy May Increase Breast Cancer Risk

by Aruna on October 14, 2009 at 11:30 AM
Font : A-A+

Breast Tenderness After Hormone Replacement Therapy May Increase Breast Cancer Risk

Researchers say that women who develop tenderness in their breasts after using hormone replacement therapy are at an increased risk of developing breast cancer.

However, it is still unknown why breast tenderness indicates increased cancer risk among women on estrogen plus progestin hormone replacement therapy.

Advertisement

"Is it because the hormone therapy is causing breast-tissue cells to multiply more rapidly, which causes breast tenderness and at the same time indicates increased cancer risk? We need to figure out what makes certain women more susceptible to developing breast tenderness during hormone therapy than other women," said Dr. Carolyn J. Crandall, a clinical professor of general internal medicine and health services research at the David Geffen School of Medicine at UCLA.

The researchers compared the daily use of oral conjugated equine estrogens (0.625 mg) plus medroxyprogesterone acetate (2.5 mg), or CEE+MPA, with the daily use of a placebo pill.
Advertisement

Among the women who did report breast tenderness at the beginning, the risk at one-year was about 1.26 times that of their counterparts on placebos.

Of the women who reported new-onset breast tenderness, 76.3 percent had been on the combination therapy.

Women in the combination therapy group who did not have breast tenderness at the outset but experienced new-onset tenderness at the first annual follow-up had a 48 percent higher risk of invasive breast cancer than their counterparts on combination therapy who did not have breast tenderness at the first-year follow-up.

The study is published in Archives of Internal Medicine.

Source: ANI
ARU
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Sensory Processing Disorder (SPD)
First Dose of COVID-19 Vaccines May Improve Mental Health
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Women and Cancer Breast Biopsy Pagets disease of the breast Mastitis Menopause Hot Flash Vaginitis Cancer and Homeopathy Dilatation and Curettage Reiki and Pranic Healing 

Recommended Reading
Hormone Replacement Therapy - Side effects and Risks
Prolonged use of HRT for more than 10 years can enhance risk of breast and uterine cancer....
Estrogen Treatment for Breast Cancer Found to be Good for Breast Cancer
Low doses of estrogen may help in the treatment of some forms of breast cancer, a recent clinical .....
Women and Cancer - Breast Cancer
Encyclopedia section of medindia gives valuable information about Breast cancer in women...
Breast Biopsy
Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or .....
Hot Flash
The frequency of the hot flash can be from 1 to 2 two hot flashes a week to 10 or greater in a day. ...
Mastitis
Mastitis is a common cause of tenderness, swelling and pain in breast, owing to inflammation in the ...
Menopause
Menopause is defined as the state of permanent cessation of menstrual cycles (periods) for ......
Pagets disease of the breast
A detailed description of the Paget's disease of the breast, characteristic signs and symptoms, dete...
Vaginitis
Vaginal infection or vaginitis occurs due to an overgrowth of bacteria or yeast or trichomoniasis ...
Women and Cancer
Cancer is one of the frequently talked about and most feared disease that falls under the genre of l...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use