About Careers MedBlog Contact us

Brain Chemical Serotonin and Growth Hormone 'TGF-Beta' Decide Dietary Impact on Aging

by Bidita Debnath on May 13, 2015 at 11:41 PM
Font : A-A+

Brain Chemical Serotonin and Growth Hormone 'TGF-Beta' Decide Dietary Impact on Aging

How does our brain interpret food signals — a process that influences the impact of diet on health and aging. Scientists have now deciphered the neural code involved.

In animal experiments, researchers from King's College London and engineers from the Georgia Institute of Technology, in the US, found that levels of brain chemical serotonin and a growth hormone known as TGF-beta communicate information about food abundance.


These signals from the nervous system influence the animal's lifespan, thus mediating the effects of food on ageing.

"It is the first time neural gene expression has been analyzed with this level of detail in a multi-cellular animal," said QueeLim Ch'ng, senior co-author of the study

Most people think about electrical activity when they think about encoding information in the nervous system.

"Our work shows that gene expression is an important, but virtually unexplored aspect of information processing in the nervous system," Ch'ng noted.

The perception of food by the nervous system impacts not just aging but also other processes associated with health and disease, including metabolism, reproduction and development.

Both serotonin and TGF-beta pathways have been implicated in diverse human diseases, including cancer, mental disorders, diabetes and obesity.

The study was published in the journal eLife.

Source: IANS


Recommended Reading

Latest Research News

What Are the Effects of T Cells on Blood Pressure and Inflammation?
A new study explored the link between T immune cells in ill patients and mortality risk.
How Does a New Procedure Help Patients Avoid Leg Amputation?
Limb savage procedure benefits patients with severe vascular disease who are at risk for amputation of their limbs.
Omega-3 Can Save Alzheimer's Patients from Vision Loss
Does omega-3 help Alzheimer's patients? A new form of omega-3 helped restore specific markers of eye health in mice bred with aspects of early-onset Alzheimer's disease.
Why Is Asthma Linked to Increased Risk of Osteoarthritis?
Drugs used to inhibit the physiological responses for allergic reactions lessen osteoarthritis risk, revealed research.
 Experiments on Child Brain Tumour and Muscle Ageing Heading to Space
The International Space Station will be used to carry out experiments seeking to improve understanding of incurable child brain tumors and the muscle aging process.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Brain Chemical Serotonin and Growth Hormone 'TGF-Beta' Decide Dietary Impact on Aging Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests