WHO grants pre-qualification status to Biological E's novel oral polio vaccine type 2. This next-gen vaccine aims to curb cVDPV2 outbreaks in affected countries.
Poliovirus vaccines
Go to source) This advanced vaccine is designed to combat the threat of circulating vaccine-derived poliovirus (1✔ ✔Trusted Source
Poliovirus vaccines
Go to source) type 2 (cVDPV2) outbreaks.
Poliomyelitis
Polio is an infectious disease caused by the poliovirus. It results in paralysis and generally affects people of all age groups, children being more susceptible
Polio is an infectious disease caused by the poliovirus. It results in paralysis and generally affects people of all age groups, children being more susceptible
‘The Hyderabad-based firm obtained the technology for the next-generation live, attenuated oral vaccine to combat #polio outbreaks from Indonesia's PT BioFarma. #drug’
Biological E Achieves Milestone with Ten WHO Pre-Qualified Vaccines
With this achievement, Biological E now boasts a portfolio of ten WHO pre-qualified vaccines. The company has established large-scale manufacturing capabilities to produce over 500 million nOPV2 doses annually, supported by a grant from the Bill & Melinda Gates Foundation.Developed in collaboration with Indonesia’s PT BioFarma, the first WHO-prequalified nOPV2 manufacturer, the vaccine has undergone rigorous clinical trials demonstrating its safety and efficacy in preventing polio. Real-world deployment has shown a significant reduction in cVDPV2 outbreaks.
“This is a crucial milestone in our global fight against polio,” said Biological E Managing Director Mahima Datla. “nOPV2 offers enhanced genetic stability, addressing concerns about Vaccine-Associated Paralytic Polio (VAPP) associated with the previous OPV.”
Post-Polio Syndrome
Post polio syndrome occurs a long time after an early attack of poliomyelitis virus. Gradual progressive weakening in muscles, fatigue, joint pain and a decrease in the size of muscles are key symptoms.
Post polio syndrome occurs a long time after an early attack of poliomyelitis virus. Gradual progressive weakening in muscles, fatigue, joint pain and a decrease in the size of muscles are key symptoms.
Reference:
- Poliovirus vaccines - (https://www.who.int/groups/global-advisory-committee-on-vaccine-safety/topics/poliovirus-vaccines)
Quiz on Polio
Polio was one of the dreaded diseases that left its victims paralyzed and disabled for life. Test your knowledge on this condition, which hopefully will soon be history! ...
Polio was one of the dreaded diseases that left its victims paralyzed and disabled for life. Test your knowledge on this condition, which hopefully will soon be history! ...
Modified Polio Vaccine Could Emerge as a Possible Treatment for Brain Cancer
The oncolytic virus PVSRIPO, an engineered hybrid of poliovirus and rhinovirus, appears to exhibit dual action against glioma cancer cells.
The oncolytic virus PVSRIPO, an engineered hybrid of poliovirus and rhinovirus, appears to exhibit dual action against glioma cancer cells.
