In patients with ischemic stroke, both acupuncture at Waiguan (SJ5) and sham acupuncture can activate/deactivate several brain regions.

Dr. Ji Qi and co-workers from School of Traditional Chinese Medicine, Southern Medical University in China examined the effects of acupuncture on brain function in a pathological context, and compared the effects between Waiguan and sham points in 16 patients with ischemic stroke.
Compared with sham acupuncture, acupuncture at Waiguan in stroke patients inhibited Brodmann area 5 on the healthy side. These findings, published in the Neural Regeneration Research (Vol. 9, No. 3, 2014), indicated that the altered specificity of sensation-associated cortex (Brodmann area 5) is possibly associated with a central mechanism of acupuncture at Waiguan for stroke patients.
Source-Eurekalert
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