Menstrual cramps, or Primary dysmenorrhea (PDM) may cause abnormal changes in the brain structure, scientists have said.

"Although the functional consequences remain to be established, these results indicate that the adolescent brain is vulnerable to menstrual pain," said Hsieh.
Researchers found significant GM (gray matter) volume changes in the patients' anatomical maps.
Abnormal decreases were found in regions involved in pain transmission, higher level sensory processing, and affect regulation while increases were found in regions involved in pain modulation and in regulation of endocrine function.
The study is scheduled for publication in the September issue of AIN.
Source-ANI
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