About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

50 MicroRNAs in Saliva That may Help Diagnose Oral Cancer Identified

by Rajashri on August 28, 2009 at 9:21 PM
Font : A-A+

 50 MicroRNAs in Saliva That may Help Diagnose Oral Cancer Identified

A new US study says that at least 50 microRNAs present in human saliva may prove helpful in detecting oral cancer.

The findings of the study have been detailed in an article published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Advertisement

"It is a Holy Grail of cancer detection to be able to measure the presence of a cancer without a biopsy, so it is very appealing to think that we could detect a cancer-specific marker in a patient's saliva," said Dr. Jennifer Grandis, professor of Otolaryngology and Pharmacology at the University of Pittsburgh School of Medicine and Cancer Institute, and a senior editor of Clinical Cancer Research.

MicroRNAs are molecules produced in cells that have the ability to simultaneously control activity and assess the behaviour of multiple genes. Scientists believe that they may hold the key to early detection of cancer.
Advertisement

The emergence of a microRNA profile in saliva represents a major step forward in the early detection of oral cancer.

"The oral cavity is a mirror to systemic health, and many diseases that develop in other parts of the body have an oral manifestation," said David T. Wong, Felix and Mildred Yip Endowed Professor at the University of California, Los Angeles School of Dentistry.uring the study, the researchers measured microRNA levels in the saliva of 50 patients with oral squamous cell carcinoma, and 50 healthy control patients.

Their efforts led to the detection of approximately 50 microRNAs, says the study report.

The article points out that two specific microRNAs-miR-125a and miR-200a-were present at significantly lower levels in patients with oral cancer than in the healthier controls.

Wong admitted that the study's findings would have to be confirmed by a larger and longer analysis.

Source: ANI
RAS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Oral Cancer Cancer and Homeopathy Cancer Facts Cancer Tattoos A Body Art Dental Check-Up Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant Head and Neck Cancers Top 7 Benefits of Good Oral Hygiene 

Recommended Reading
Health Hazards of Smoking
Smoking causes many diseases and affects the overall health of smokers....
Smoking Increases Risk of Developing Active TB
Smoking is a risk factor for active tuberculosis (TB) disease, according to a new study on TB ......
Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most...
Dental Check-Up
It is commonly recommended that you visit the dentist twice a year to clean your teeth and gums and ...
Head and Neck Cancers
Head and neck cancers usually occur in the squamous cells lining the moist, mucosal surfaces inside ...
Health Benefits of Dandelion Plant
What is dandelion? Dandelion greens are nutrition powerhouses with a wide range of health benefits. ...
Oral Cancer
Oral cancer is a cancer that develops in any part of the mouth. It is more common in men over 40....
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...
Top 7 Benefits of Good Oral Hygiene
Practicing good oral hygiene regularly is a good investment not only for teeth but also for overall ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use