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| Abbreviation | Expansion |
| O & P | Ova and Parasites |
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| O2 | Oxygen |
| OBS | Organic Brain Syndrome |
| OCD | Obsessive Compulsive Disorder |
| OCG | Oral cholecystogram |
| OD | Overdose |
| OD | Oculus dexter, Right Eye |
| OGTT | Oral Glucose Tolerance Test |
| OMS | Organic Mental Syndrome |
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| OOB | Out of Bed |
| OP | Osmotic Pressure, Outpatient |
| OPA | Oropharyngeal Airway |
| OPV | Oral polio vaccine |
| ORD | Optical Rotatory Dispersion |
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| ORIF | Open Reduction and Internal Fixation |
| ORIF | Open Reduction Internal Fixation |
| OS | Oculus sinister, Left Eye |
| OSHA | Occupational Safety and Health Administration |
| OT | Occupational Therapy, Occupational Therapist |
| OU | Oculus uterque, Both Eyes |
| Abbreviation | Expansion |
| OD | Doctor of Osteopathy |
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