Lancet Haematol
Tumour lysis syndrome in patients with chronic lymphocytic leukaemia treated with BCL-2 inhibitors: risk factors, prophylaxis, and treatment recommendations.
Tambaro FP, Wierda WG
Tumour lysis syndrome is a complication of chemotherapy for haematological malignancies; in particular, aggressive leukaemias and lymphomas. For haema ...
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Source: PubMed
Cardiovasc Hematol Disord Drug Targets 2020 Jan 29
Co-existence of follicular lymphoma in the lymph node with High-grade B cell lymphoma in the bone marrow of a patient presenting with spontaneous tumor lysis syndrome.
Giatra C, Sykaras AG, Constantinou F, Gennimata V, Sampaziotis D, Geladari E, Kounatidis D, Vallianou NG
A significant percentage of B-cell lymphomas are characterized by bone marrow involvement (BMI) at diagnosis. In most cases, there is concordance betw ...
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Source: PubMed
Hematol Oncol 2020 Jan 27
Anti-rasburicase antibodies induce clinical refractoriness by inhibiting the enzyme catalytic activity.
Moia R, Boggio E, Gigliotti L, Crisà E, De Paoli L, Margiotta Casaluci G, Rolla R, Patriarca A, Gaidano G, Dianzani U, Bruna R
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Source: PubMed
Ann. Hematol. 2020 Jan 21
Cytogenetics and mutations could predict outcome in relapsed and refractory acute myeloid leukemia patients receiving BCL-2 inhibitor venetoclax.
Wang YW, Tsai CH, Lin CC, Tien FM, Chen YW, Lin HY, Yao M, Lin YC, Lin CT, Cheng CL, Tang JL, Chou WC, Hou HA, Tien HF
Venetoclax, a selective B cell leukemia/lymphoma-2 (BCL2) inhibitor, has recently shown activity in relapsed or refractory (R/R) acute myeloid leukemi ...
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Source: PubMed
Case Rep Crit Care
Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?
Tarcukovic J, Valencic L, Polonijo Ž, Fucak A, Dangubic B, Grubješic I
Tumour lysis syndrome (TLS) is a group of pathophysiological processes caused by rapid degradation of tumour cells with subsequent release of intracel ...
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Source: PubMed
