Biochimie 2020 Jan 28
Calreticulin protects insulin against reductive stress in vitro and in MIN6 cells.
Ikezaki M, Minakata S, Nishitsuji K, Tabata S, Lee Matsui IS, Takatani M, Usukura J, Ito Y, Ihara Y
Oxidative folding of proinsulin in the endoplasmic reticulum (ER) is critical for the proper sorting and secretion of insulin from pancreatic ß-cells. ...
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Source: PubMed
Gut Liver 2020 Feb 03
Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasound for the Guidance and Monitoring of Endoscopic Radiofrequency Ablation.
Choi JH, Seo DW, Song TJ, Park DH, Lee SS, Lee SK, Kim MH
Background/Aims: Interventional endoscopists may utilize contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) for image guidance during radiofre ...
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Source: PubMed
Biochem. Biophys. Res. Commun. 2020 Jan 21
The role of bone-derived PDGF-AA in age-related pancreatic ß cell proliferation and function.
Liu X, Zhang F, Chai Y, Wang L, Yu B
The occurrence of type 2 diabetes(T2D) increases with age. The platelet-derived growth factor (PDGF) is one of the key factors regulating ß cell proli ...
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Source: PubMed
J. Pharm. Pharmacol. 2020 Jan 24
Investigation of cell death mechanism and activity of esculetin-loaded PLGA nanoparticles on insulinoma cells in vitro.
Karatug Kacar A, Bahadori F, Kepekci Tekkeli SE, Topcu G, Bolkent S
The purpose of this study was to prepare targeted cancer therapy formulation against insulinoma INS-1 cells and to study its effect on cell death with ...
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Source: PubMed
Cancer Cytopathol 2020 Jan 24
Insulinoma-associated protein 1 (INSM1) is a robust marker for identifying and grading pancreatic neuroendocrine tumors.
Kim D, Viswanathan K, Goyal A, Rao R
Pancreatic neuroendocrine tumor (PNET) is a diagnostic challenge with limited samples in not only identification but grading. Prior studies have shown ...
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Source: PubMed
