Alzheimer''s disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.
Cognitively normal adults exhibiting atrophy of their temporal lobe or damage to blood vessels in the brain are more likely to develop Alzheimer's disease.
Single strand breaks are one of the most common types of DNA damage and could help spot other rare DNA repair related diseases.
Chronic HIV infection and amyloid deposition with aging may represent a double-hit to the brain that results in progressive dementia.