Side effect(s) of Naldemedine

Review the side-effects of Naldemedine as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Common: Diarrhea, nausea, stomach pain

  Gastrointestinal: Gastroenteritis, vomiting, loss of appetite, perforation of the digestive tract, bloody stools

  Central nervous system: Symptoms of opioid withdrawal which may include increased sweating or tear formation, chills, flushing, increase in heart rate, fever, sneezing, yawning, anxiety, agitation, tremor, abdominal pain, diarrhea, nausea, and vomiting.

  Allergic reaction: Hives, itching, trouble with breathing, chest tightness or bronchospasm

Other Precautions :

• The risk-benefit ratio must be considered in patients who are treated with naldemedine because of the possibility of digestive tract perforation or the opioid withdrawal symptoms.