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Darifenacin Interaction with other Drugs


Darifenacin is a muscarinic receptor antagonist, prescribed for overactive bladder with symptoms of urinary incontinence, urgency and frequency.

Darifenacin Interaction with 439 drugs. Find out more in the list below:

Abiraterone


The serum concentration of Darifenacin can be increased when it is combined with Abiraterone.

abobotulinumtoxinA


Darifenacin may increase the anticholinergic activities of Botulinum Toxin Type A.

Acetaminophen


The metabolism of Acetaminophen can be decreased when combined with Darifenacin.

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Acetylcholine


The metabolism of Acetylcholine can be decreased when combined with Darifenacin.

Acetylcholine Chloride


The metabolism of Acetylcholine can be decreased when combined with Darifenacin.

Aclidinium


Darifenacin may increase the anticholinergic activities of Aclidinium.

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Ajmaline


The metabolism of Ajmaline can be decreased when combined with Darifenacin.

Alfentanil


The risk or severity of adverse effects can be increased when Darifenacin is combined with Alfentanil.

Almotriptan


The metabolism of Almotriptan can be decreased when combined with Darifenacin.

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Alogliptin


The metabolism of Alogliptin can be decreased when combined with Darifenacin.

Alphaprodine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Alphaprodine.

Alprenolol


The metabolism of Alprenolol can be decreased when combined with Darifenacin.

Ambenonium


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Ambenonium.

Aminopyrine


The metabolism of Aminophenazone can be decreased when combined with Darifenacin.

Amiodarone


The metabolism of Darifenacin can be decreased when combined with Amiodarone.

Amitriptyline


The metabolism of Amitriptyline can be decreased when combined with Darifenacin.

Amoxapine


The metabolism of Amoxapine can be decreased when combined with Darifenacin.

Amphetamine


The metabolism of Amphetamine can be decreased when combined with Darifenacin.

Amprenavir


The metabolism of Amprenavir can be decreased when combined with Darifenacin.

Amsacrine


The metabolism of Amsacrine can be decreased when combined with Darifenacin.

Antipyrine


The metabolism of Antipyrine can be decreased when combined with Darifenacin.

Apalutamide


The serum concentration of Darifenacin can be decreased when it is combined with Apalutamide.

Aprepitant


The serum concentration of Darifenacin can be increased when it is combined with Aprepitant.

Aprindine


The metabolism of Aprindine can be decreased when combined with Darifenacin.

Arformoterol


The metabolism of Arformoterol can be decreased when combined with Darifenacin.

Aripiprazole


The serum concentration of Aripiprazole can be increased when it is combined with Darifenacin.

Artemether


The metabolism of Artemether can be decreased when combined with Darifenacin.

Astemizole


The metabolism of Astemizole can be decreased when combined with Darifenacin.

Atazanavir


The metabolism of Darifenacin can be decreased when combined with Atazanavir.

Atomoxetine


The metabolism of Darifenacin can be decreased when combined with Atomoxetine.

Atracurium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Atracurium.

Atracurium Besylate


The risk or severity of adverse effects can be increased when Darifenacin is combined with Atracurium besylate.

Atropine


The risk or severity of adverse effects can be increased when Atropine is combined with Darifenacin.

Azelastine


The metabolism of Azelastine can be decreased when combined with Darifenacin.

Benactyzine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Benactyzine.

Bendroflumethiazide


The serum concentration of Bendroflumethiazide can be increased when it is combined with Darifenacin.

Benztropine


The risk or severity of adverse effects can be increased when Benzatropine is combined with Darifenacin.

Benzyl Alcohol


The metabolism of Benzyl alcohol can be decreased when combined with Darifenacin.

Bepridil


The metabolism of Bepridil can be decreased when combined with Darifenacin.

Betaxolol


The metabolism of Betaxolol can be decreased when combined with Darifenacin.

Biperiden


The risk or severity of adverse effects can be increased when Biperiden is combined with Darifenacin.

Bisoprolol


The metabolism of Bisoprolol can be decreased when combined with Darifenacin.

Boceprevir


The metabolism of Darifenacin can be decreased when combined with Boceprevir.

Bortezomib


The metabolism of Darifenacin can be decreased when combined with Bortezomib.

Bosentan


The serum concentration of Darifenacin can be decreased when it is combined with Bosentan.

Botulinum Toxin Type A


Darifenacin may increase the anticholinergic activities of Botulinum Toxin Type A.

Brexpiprazole


The serum concentration of Brexpiprazole can be increased when it is combined with Darifenacin.

Brigatinib


The serum concentration of Darifenacin can be decreased when it is combined with Brigatinib.

Brompheniramine


The metabolism of Brompheniramine can be decreased when combined with Darifenacin.

Bupivacaine


The metabolism of Bupivacaine can be decreased when combined with Darifenacin.

Buprenorphine


The metabolism of Buprenorphine can be decreased when combined with Darifenacin.

Bupropion


The metabolism of Darifenacin can be decreased when combined with Bupropion.

Buspirone


The metabolism of Buspirone can be decreased when combined with Darifenacin.

Butorphanol


The risk or severity of adverse effects can be increased when Darifenacin is combined with Butorphanol.

Butylscopolamine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Butylscopolamine.

Caffeine


The metabolism of Caffeine can be decreased when combined with Darifenacin.

Captopril


The metabolism of Captopril can be decreased when combined with Darifenacin.

Carbamazepine


The metabolism of Darifenacin can be increased when combined with Carbamazepine.

Cariprazine


The metabolism of Cariprazine can be decreased when combined with Darifenacin.

Carteolol


The metabolism of Carteolol can be decreased when combined with Darifenacin.

Carvedilol


The metabolism of Carvedilol can be decreased when combined with Darifenacin.

Celecoxib


The metabolism of Darifenacin can be decreased when combined with Celecoxib.

Cephalexin


The metabolism of Cephalexin can be decreased when combined with Darifenacin.

CEPHALEXIN ANHYDROUS


The metabolism of Cephalexin can be decreased when combined with Darifenacin.

Ceritinib


The serum concentration of Darifenacin can be increased when it is combined with Ceritinib.

Cevimeline


The metabolism of Cevimeline can be decreased when combined with Darifenacin.

Chlordiazepoxide


The metabolism of Chlordiazepoxide can be decreased when combined with Darifenacin.

Chloroquine


The metabolism of Chloroquine can be decreased when combined with Darifenacin.

Chlorothiazide


The serum concentration of Chlorothiazide can be increased when it is combined with Darifenacin.

Chlorpheniramine


The metabolism of Chlorphenamine can be decreased when combined with Darifenacin.

CHLORPHENIRAMINE POLISTIREX


The metabolism of Chlorphenamine can be decreased when combined with Darifenacin.

Chlorphenoxamine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Chlorphenoxamine.

Chlorpromazine


The metabolism of Darifenacin can be decreased when combined with Chlorpromazine.

Chlorthalidone


The serum concentration of Chlorthalidone can be increased when it is combined with Darifenacin.

Chlorzoxazone


The metabolism of Chlorzoxazone can be decreased when combined with Darifenacin.

Cholecalciferol


The metabolism of Darifenacin can be decreased when combined with Cholecalciferol.

Cilostazol


The metabolism of Cilostazol can be decreased when combined with Darifenacin.

Cimetidine


The metabolism of Darifenacin can be decreased when combined with Cimetidine.

Cinacalcet


The metabolism of Darifenacin can be decreased when combined with Cinacalcet.

Cinnarizine


The metabolism of Cinnarizine can be decreased when combined with Darifenacin.

Citalopram


The metabolism of Citalopram can be decreased when combined with Darifenacin.

Clarithromycin


The metabolism of Darifenacin can be decreased when combined with Clarithromycin.

Clemastine


The metabolism of Darifenacin can be decreased when combined with Clemastine.

Clevidipine


The metabolism of Clevidipine can be decreased when combined with Darifenacin.

Clevidipine butyrate


The metabolism of Clevidipine can be decreased when combined with Darifenacin.

Clobazam


The metabolism of Darifenacin can be decreased when combined with Clobazam.

Clomipramine


The metabolism of Clomipramine can be decreased when combined with Darifenacin.

Clonidine


The metabolism of Clonidine can be decreased when combined with Darifenacin.

Clotrimazole


The metabolism of Darifenacin can be decreased when combined with Clotrimazole.

Clozapine


The metabolism of Clozapine can be decreased when combined with Darifenacin.

Cobicistat


The serum concentration of Darifenacin can be increased when it is combined with Cobicistat.

Cocaine


The metabolism of Darifenacin can be decreased when combined with Cocaine.

Codeine


The therapeutic efficacy of Codeine can be decreased when used in combination with Darifenacin.

Codeine Anhydrous


The therapeutic efficacy of Codeine can be decreased when used in combination with Darifenacin.

CODEINE POLISTIREX


The therapeutic efficacy of Codeine can be decreased when used in combination with Darifenacin.

Conivaptan


The serum concentration of Conivaptan can be increased when it is combined with Darifenacin.

Crizotinib


The metabolism of Darifenacin can be decreased when combined with Crizotinib.

Cyclobenzaprine


The metabolism of Cyclobenzaprine can be decreased when combined with Darifenacin.

Cyclopenthiazide


The serum concentration of Cyclopenthiazide can be increased when it is combined with Darifenacin.

Cyclopentolate


The risk or severity of adverse effects can be increased when Cyclopentolate is combined with Darifenacin.

Cyclophosphamide


The metabolism of Cyclophosphamide can be decreased when combined with Darifenacin.

Cyclophosphamide Anhydrous


The metabolism of Cyclophosphamide can be decreased when combined with Darifenacin.

Cyclosporine


The metabolism of Darifenacin can be decreased when combined with Cyclosporine.

Dabrafenib


The serum concentration of Darifenacin can be decreased when it is combined with Dabrafenib.

Dapagliflozin


The metabolism of Dapagliflozin can be decreased when combined with Darifenacin.

Darunavir


The serum concentration of Darifenacin can be increased when it is combined with Darunavir.

Dasabuvir


The metabolism of Dasabuvir can be decreased when combined with Darifenacin.

Dasatinib


The serum concentration of Darifenacin can be increased when it is combined with Dasatinib.

Dasatinib Anhydrous


The serum concentration of Darifenacin can be increased when it is combined with Dasatinib.

Debrisoquin


The metabolism of Debrisoquin can be decreased when combined with Darifenacin.

Deferasirox


The serum concentration of Darifenacin can be decreased when it is combined with Deferasirox.

Delavirdine


The metabolism of Darifenacin can be decreased when combined with Delavirdine.

Demecarium


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Demecarium.

Desipramine


The metabolism of Desipramine can be decreased when combined with Darifenacin.

Desloratadine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Desloratadine.

Deutetrabenazine


The metabolism of Deutetrabenazine can be decreased when combined with Darifenacin.

Dexchlorpheniramine maleate


The metabolism of Dexchlorpheniramine maleate can be decreased when combined with Darifenacin.

Dexetimide


The risk or severity of adverse effects can be increased when Dexetimide is combined with Darifenacin.

Dexfenfluramine


The metabolism of Dexfenfluramine can be decreased when combined with Darifenacin.

Dexmethylphenidate


The metabolism of Dexmethylphenidate can be decreased when combined with Darifenacin.

Dextroamphetamine


The metabolism of Dextroamphetamine can be decreased when combined with Darifenacin.

Dextromethorphan


The metabolism of Dextromethorphan can be decreased when combined with Darifenacin.

Dextromoramide


The risk or severity of adverse effects can be increased when Darifenacin is combined with Dextromoramide.

Dezocine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Dezocine.

Dicyclomine


The risk or severity of adverse effects can be increased when Dicyclomine is combined with Darifenacin.

Dihydrocodeine


The metabolism of Dihydrocodeine can be decreased when combined with Darifenacin.

Dihydroergotamine


The metabolism of Darifenacin can be decreased when combined with Dihydroergotamine.

Diltiazem


The metabolism of Darifenacin can be decreased when combined with Diltiazem.

Diphenhydramine


The metabolism of Diphenhydramine can be decreased when combined with Darifenacin.

Diphenoxylate


The risk or severity of adverse effects can be increased when Darifenacin is combined with Diphenoxylate.

Distigmine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Distigmine.

Dolasetron


The metabolism of Dolasetron can be decreased when combined with Darifenacin.

Domperidone


The metabolism of Domperidone can be decreased when combined with Darifenacin.

Donepezil


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Donepezil.

Dopamine


The metabolism of Dopamine can be decreased when combined with Darifenacin.

Dothiepin


The metabolism of Darifenacin can be decreased when combined with Dosulepin.

Doxazosin


The metabolism of Doxazosin can be decreased when combined with Darifenacin.

Doxepin


The metabolism of Doxepin can be decreased when combined with Darifenacin.

Doxorubicin


The serum concentration of Doxorubicin can be increased when it is combined with Darifenacin.

Doxorubicin Hydrochloride


The serum concentration of Doxorubicin can be increased when it is combined with Darifenacin.

Doxycycline


The metabolism of Darifenacin can be decreased when combined with Doxycycline.

Doxycycline Anhydrous


The metabolism of Darifenacin can be decreased when combined with Doxycycline.

Dronedarone


The metabolism of Darifenacin can be decreased when combined with Dronedarone.

Duloxetine


The metabolism of Darifenacin can be decreased when combined with Duloxetine.

Echothiophate


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Echothiophate.

Edrophonium


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Edrophonium.

Eletriptan


The metabolism of Eletriptan can be decreased when combined with Darifenacin.

Eliglustat


The serum concentration of Eliglustat can be increased when it is combined with Darifenacin.

Eluxadoline


Darifenacin may increase the constipating activities of Eluxadoline.

Enasidenib


The metabolism of Enasidenib can be decreased when combined with Darifenacin.

Encainide


The metabolism of Encainide can be decreased when combined with Darifenacin.

Enzalutamide


The serum concentration of Darifenacin can be decreased when it is combined with Enzalutamide.

Epinastine


The metabolism of Epinastine can be decreased when combined with Darifenacin.

Erlotinib


The metabolism of Erlotinib can be decreased when combined with Darifenacin.

Erythromycin


The metabolism of Darifenacin can be decreased when combined with Erythromycin.

Escitalopram


The metabolism of Escitalopram can be decreased when combined with Darifenacin.

Ethylmorphine


The metabolism of Ethylmorphine can be decreased when combined with Darifenacin.

Etoricoxib


The metabolism of Etoricoxib can be decreased when combined with Darifenacin.

Fentanyl


The risk or severity of adverse effects can be increased when Darifenacin is combined with Fentanyl.

Fesoterodine


The serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Darifenacin.

Fingolimod


The metabolism of Fingolimod can be decreased when combined with Darifenacin.

Flecainide


The metabolism of Flecainide can be decreased when combined with Darifenacin.

Fluconazole


The metabolism of Darifenacin can be decreased when combined with Fluconazole.

Flunarizine


The metabolism of Flunarizine can be decreased when combined with Darifenacin.

Fluoxetine


The metabolism of Darifenacin can be decreased when combined with Fluoxetine.

Fluphenazine


The metabolism of Fluphenazine can be decreased when combined with Darifenacin.

Fluvastatin


The metabolism of Fluvastatin can be decreased when combined with Darifenacin.

Fluvoxamine


The metabolism of Darifenacin can be decreased when combined with Fluvoxamine.

Formoterol


The metabolism of Formoterol can be decreased when combined with Darifenacin.

Fosamprenavir


The metabolism of Darifenacin can be decreased when combined with Fosamprenavir.

Fosaprepitant


The serum concentration of Darifenacin can be increased when it is combined with Fosaprepitant.

Fosphenytoin


The metabolism of Darifenacin can be increased when combined with Fosphenytoin.

Fusidate


The serum concentration of Darifenacin can be increased when it is combined with Fusidic Acid.

Fusidic Acid


The serum concentration of Darifenacin can be increased when it is combined with Fusidic Acid.

Galantamine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Galantamine.

Gallamine Triethiodide


The risk or severity of adverse effects can be increased when Gallamine Triethiodide is combined with Darifenacin.

Gefitinib


The metabolism of Gefitinib can be decreased when combined with Darifenacin.

Ginkgo biloba extract


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Ginkgo biloba.

Glucagon


The risk or severity of adverse effects can be increased when Darifenacin is combined with Glucagon recombinant.

glucagon (rDNA)


The risk or severity of adverse effects can be increased when Darifenacin is combined with Glucagon recombinant.

Glycopyrronium


Darifenacin may increase the anticholinergic activities of Glycopyrronium.

Granisetron


The metabolism of Granisetron can be decreased when combined with Darifenacin.

Halofantrine


The metabolism of Halofantrine can be decreased when combined with Darifenacin.

Haloperidol


The metabolism of Haloperidol can be decreased when combined with Darifenacin.

Halothane


The metabolism of Halothane can be decreased when combined with Darifenacin.

Heroin


The risk or severity of adverse effects can be increased when Darifenacin is combined with Heroin.

Homatropine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Homatropine.

Human Secretin


The therapeutic efficacy of Human secretin can be decreased when used in combination with Darifenacin.

Hydrochlorothiazide


The serum concentration of Hydrochlorothiazide can be increased when it is combined with Darifenacin.

Hydrocodone


The metabolism of Hydrocodone can be decreased when combined with Darifenacin.

HYDROCODONE POLISTIREX


The metabolism of Hydrocodone can be decreased when combined with Darifenacin.

Hydroflumethiazide


The serum concentration of Hydroflumethiazide can be increased when it is combined with Darifenacin.

Hydromorphone


The metabolism of Hydromorphone can be decreased when combined with Darifenacin.

Hyoscyamine


The risk or severity of adverse effects can be increased when Hyoscyamine is combined with Darifenacin.

Hypoxis hemerocallidea root extract


The serum concentration of Darifenacin can be decreased when it is combined with St. John's Wort.

Ibrutinib


The metabolism of Ibrutinib can be decreased when combined with Darifenacin.

Idarubicin


The metabolism of Idarubicin can be decreased when combined with Darifenacin.

Idelalisib


The serum concentration of Darifenacin can be increased when it is combined with Idelalisib.

Iloperidone


The metabolism of Iloperidone can be decreased when combined with Darifenacin.

Imatinib


The metabolism of Darifenacin can be decreased when combined with Imatinib.

Imipramine


The metabolism of Imipramine can be decreased when combined with Darifenacin.

incobotulinumtoxinA


Darifenacin may increase the anticholinergic activities of Botulinum Toxin Type A.

Indapamide


The serum concentration of Indapamide can be increased when it is combined with Darifenacin.

Indinavir


The metabolism of Darifenacin can be decreased when combined with Indinavir.

INDINAVIR ANHYDROUS


The metabolism of Darifenacin can be decreased when combined with Indinavir.

Ipratropium Bromide


The risk or severity of adverse effects can be increased when Ipratropium bromide is combined with Darifenacin.

Ipratropium Bromide Anhydrous


The risk or severity of adverse effects can be increased when Ipratropium bromide is combined with Darifenacin.

Isavuconazole


The serum concentration of Darifenacin can be increased when it is combined with Isavuconazole.

Isavuconazonium


The metabolism of Darifenacin can be decreased when combined with Isavuconazonium.

Isoflurophate


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Isoflurophate.

Isoniazid


The metabolism of Darifenacin can be decreased when combined with Isoniazid.

Isradipine


The metabolism of Darifenacin can be decreased when combined with Isradipine.

Itraconazole


The metabolism of Darifenacin can be decreased when combined with Itraconazole.

Ivacaftor


The serum concentration of Darifenacin can be increased when it is combined with Ivacaftor.

Ixazomib


The metabolism of Ixazomib can be decreased when combined with Darifenacin.

Ketoconazole


The metabolism of Darifenacin can be decreased when combined with Ketoconazole.

Labetalol


The metabolism of Labetalol can be decreased when combined with Darifenacin.

Letermovir


The metabolism of Letermovir can be decreased when combined with Darifenacin.

Levodopa


The metabolism of Levodopa can be decreased when combined with Darifenacin.

Levomethadyl


The risk or severity of adverse effects can be increased when Darifenacin is combined with Levomethadyl Acetate.

Levomilnacipran


The metabolism of Levomilnacipran can be decreased when combined with Darifenacin.

Levorphanol


The risk or severity of adverse effects can be increased when Darifenacin is combined with Levorphanol.

Lidocaine


The metabolism of Lidocaine can be decreased when combined with Darifenacin.

Lisuride


The metabolism of Lisuride can be decreased when combined with Darifenacin.

Lomustine


The metabolism of Lomustine can be decreased when combined with Darifenacin.

Loperamide


The metabolism of Loperamide can be decreased when combined with Darifenacin.

Lopinavir


The metabolism of Darifenacin can be decreased when combined with Lopinavir.

Loratadine


The metabolism of Loratadine can be decreased when combined with Darifenacin.

Lorcaserin


The metabolism of Lorcaserin can be decreased when combined with Darifenacin.

Lovastatin


The metabolism of Darifenacin can be decreased when combined with Lovastatin.

Luliconazole


The serum concentration of Darifenacin can be increased when it is combined with Luliconazole.

Lumacaftor


The metabolism of Darifenacin can be increased when combined with Lumacaftor.

Lumefantrine


The metabolism of Darifenacin can be decreased when combined with Lumefantrine.

Malathion


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Malathion.

Manidipine


The metabolism of Darifenacin can be decreased when combined with Manidipine.

Maprotiline


The metabolism of Maprotiline can be decreased when combined with Darifenacin.

Mecamylamine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Mecamylamine.

Mefloquine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Mefloquine.

Memantine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Memantine.

Meperidine


The metabolism of Pethidine can be decreased when combined with Darifenacin.

Mephenytoin


The metabolism of Mephenytoin can be decreased when combined with Darifenacin.

Mequitazine


The metabolism of Mequitazine can be decreased when combined with Darifenacin.

Mesoridazine


The metabolism of Mesoridazine can be decreased when combined with Darifenacin.

Methadone


The metabolism of Methadone can be decreased when combined with Darifenacin.

Methadyl Acetate


The risk or severity of adverse effects can be increased when Darifenacin is combined with Methadyl Acetate.

Methamphetamine


The metabolism of Methamphetamine can be decreased when combined with Darifenacin.

Methantheline


The risk or severity of adverse effects can be increased when Darifenacin is combined with Methantheline.

Methixene


The risk or severity of adverse effects can be increased when Darifenacin is combined with Metixene.

Methotrimeprazine


The metabolism of Darifenacin can be decreased when combined with Methotrimeprazine.

Methoxyflurane


The metabolism of Methoxyflurane can be decreased when combined with Darifenacin.

Methscopolamine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Methscopolamine.

Methscopolamine Bromide


The risk or severity of adverse effects can be increased when Darifenacin is combined with Methylscopolamine bromide.

Methyclothiazide


The serum concentration of Methyclothiazide can be increased when it is combined with Darifenacin.

Methylphenidate


The metabolism of Methylphenidate can be decreased when combined with Darifenacin.

Methyprylon


The metabolism of Methyprylon can be decreased when combined with Darifenacin.

Metoclopramide


The metabolism of Metoclopramide can be decreased when combined with Darifenacin.

Metolazone


The serum concentration of Metolazone can be increased when it is combined with Darifenacin.

Metoprolol


The serum concentration of Metoprolol can be increased when it is combined with Darifenacin.

Mexiletine


The metabolism of Mexiletine can be decreased when combined with Darifenacin.

Mianserin


Mianserin may increase the anticholinergic activities of Darifenacin.

Midostaurin


The metabolism of Darifenacin can be decreased when combined with Midostaurin.

Mifepristone


The serum concentration of Darifenacin can be increased when it is combined with Mifepristone.

Minaprine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Minaprine.

Mirabegron


The risk or severity of adverse effects can be increased when Darifenacin is combined with Mirabegron.

Mirtazapine


The metabolism of Mirtazapine can be decreased when combined with Darifenacin.

Mitotane


The serum concentration of Darifenacin can be decreased when it is combined with Mitotane.

Moclobemide


The metabolism of Moclobemide can be decreased when combined with Darifenacin.

Morphine


The metabolism of Morphine can be decreased when combined with Darifenacin.

Nabilone


Darifenacin may increase the tachycardic activities of Nabilone.

Nalbuphine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Nalbuphine.

Nateglinide


The metabolism of Nateglinide can be decreased when combined with Darifenacin.

Nebivolol


The serum concentration of Nebivolol can be increased when it is combined with Darifenacin.

Nefazodone


The metabolism of Darifenacin can be decreased when combined with Nefazodone.

Nelfinavir


The metabolism of Darifenacin can be decreased when combined with Nelfinavir.

Neostigmine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Neostigmine.

Netupitant


The serum concentration of Darifenacin can be increased when it is combined with Netupitant.

Nevirapine


The metabolism of Darifenacin can be increased when combined with Nevirapine.

Nicardipine


The metabolism of Nicardipine can be decreased when combined with Darifenacin.

Nicergoline


The metabolism of Nicergoline can be decreased when combined with Darifenacin.

Nicotine


The metabolism of Nicotine can be decreased when combined with Darifenacin.

Nicotine Polacrilex


The metabolism of Nicotine can be decreased when combined with Darifenacin.

Nifedipine


The metabolism of Nifedipine can be decreased when combined with Darifenacin.

Nilotinib


The metabolism of Darifenacin can be decreased when combined with Nilotinib.

Nitrofurazone


The metabolism of Nitrofural can be decreased when combined with Darifenacin.

Normethadone


The risk or severity of adverse effects can be increased when Darifenacin is combined with Normethadone.

Nortriptyline


The metabolism of Nortriptyline can be decreased when combined with Darifenacin.

O-PHENANTHROLINE


The therapeutic efficacy of Darifenacin can be decreased when used in combination with 1,10-Phenanthroline.

Octotropine Methylbromide


The risk or severity of adverse effects can be increased when Darifenacin is combined with Anisotropine Methylbromide.

Octylonium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Otilonium.

Olanzapine


The metabolism of Olanzapine can be decreased when combined with Darifenacin.

Olaparib


The metabolism of Darifenacin can be decreased when combined with Olaparib.

onabotulinumtoxinA


Darifenacin may increase the anticholinergic activities of Botulinum Toxin Type A.

Ondansetron


The metabolism of Ondansetron can be decreased when combined with Darifenacin.

Opium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Opium.

Orphenadrine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Orphenadrine.

Osimertinib


The serum concentration of Darifenacin can be increased when it is combined with Osimertinib.

Oxitropium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Oxitropium.

Oxybutynin


The risk or severity of adverse effects can be increased when Darifenacin is combined with Oxybutynin.

Oxycodone


The metabolism of Oxycodone can be decreased when combined with Darifenacin.

Oxymorphone


The metabolism of Oxymorphone can be decreased when combined with Darifenacin.

Oxyphenonium


The risk or severity of adverse effects can be increased when Oxyphenonium is combined with Darifenacin.

Palbociclib


The serum concentration of Darifenacin can be increased when it is combined with Palbociclib.

Palonosetron


The metabolism of Palonosetron can be decreased when combined with Darifenacin.

Pancuronium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Pancuronium.

Pancuronium Bromide


The risk or severity of adverse effects can be increased when Darifenacin is combined with Pancuronium.

Panobinostat


The serum concentration of Darifenacin can be increased when it is combined with Panobinostat.

Paregoric


The metabolism of Morphine can be decreased when combined with Darifenacin.

Paroxetine


The metabolism of Darifenacin can be decreased when combined with Paroxetine.

Pazopanib


The metabolism of Pazopanib can be decreased when combined with Darifenacin.

Peginterferon Alfa-2b


The serum concentration of Darifenacin can be decreased when it is combined with Peginterferon alfa-2b.

Pentamidine


The metabolism of Pentamidine can be decreased when combined with Darifenacin.

Pentazocine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Pentazocine.

Pentobarbital


The metabolism of Darifenacin can be increased when combined with Pentobarbital.

Perhexiline


The metabolism of Perhexiline can be decreased when combined with Darifenacin.

Perphenazine


The metabolism of Perphenazine can be decreased when combined with Darifenacin.

Phenacetin


The metabolism of Phenacetin can be decreased when combined with Darifenacin.

Phenformin


The metabolism of Phenformin can be decreased when combined with Darifenacin.

Phenobarbital


The metabolism of Darifenacin can be increased when combined with Phenobarbital.

Phenytoin


The metabolism of Darifenacin can be increased when combined with Phenytoin.

Physostigmine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Physostigmine.

Pindolol


The metabolism of Pindolol can be decreased when combined with Darifenacin.

Pipecuronium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Pipecuronium.

Piperazine


The metabolism of Piperazine can be decreased when combined with Darifenacin.

Pipothiazine


The metabolism of Pipotiazine can be decreased when combined with Darifenacin.

Pirenzepine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Pirenzepine.

Pirinitramide


The risk or severity of adverse effects can be increased when Darifenacin is combined with Piritramide.

Polythiazide


The serum concentration of Polythiazide can be increased when it is combined with Darifenacin.

Ponatinib


The metabolism of Ponatinib can be decreased when combined with Darifenacin.

Posaconazole


The metabolism of Darifenacin can be decreased when combined with Posaconazole.

Potassium Chloride


Darifenacin may increase the ulcerogenic activities of Potassium Chloride.

Pramlintide


Pramlintide may increase the anticholinergic activities of Darifenacin.

Primidone


The metabolism of Darifenacin can be increased when combined with Primidone.

Procainamide


The metabolism of Procainamide can be decreased when combined with Darifenacin.

Prochlorperazine


The metabolism of Prochlorperazine can be decreased when combined with Darifenacin.

Procyclidine


The risk or severity of adverse effects can be increased when Procyclidine is combined with Darifenacin.

Profenamine


The risk or severity of adverse effects can be increased when Ethopropazine is combined with Darifenacin.

Progesterone


The metabolism of Progesterone can be decreased when combined with Darifenacin.

Promazine


The metabolism of Darifenacin can be decreased when combined with Promazine.

Promethazine


The metabolism of Promethazine can be decreased when combined with Darifenacin.

Propafenone


The serum concentration of Darifenacin can be increased when it is combined with Propafenone.

Propantheline


The risk or severity of adverse effects can be increased when Propantheline is combined with Darifenacin.

Propantheline Bromide


The risk or severity of adverse effects can be increased when Propantheline is combined with Darifenacin.

Propiverine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Propiverine.

Propofol


The metabolism of Propofol can be decreased when combined with Darifenacin.

Propoxyphene


The risk or severity of adverse effects can be increased when Darifenacin is combined with Dextropropoxyphene.

Propranolol


The metabolism of Propranolol can be decreased when combined with Darifenacin.

Protriptyline


The metabolism of Protriptyline can be decreased when combined with Darifenacin.

Pseudoephedrine


The metabolism of Pseudoephedrine can be decreased when combined with Darifenacin.

Pyridostigmine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Pyridostigmine.

Pyridostigmine Bromide


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Pyridostigmine.

Quetiapine


The metabolism of Quetiapine can be decreased when combined with Darifenacin.

Quetiapine fumarate


The metabolism of Quetiapine can be decreased when combined with Darifenacin.

Quinethazone


The serum concentration of Quinethazone can be increased when it is combined with Darifenacin.

Quinidine


The metabolism of Darifenacin can be decreased when combined with Quinidine.

Quinine


The metabolism of Quinine can be decreased when combined with Darifenacin.

Ranitidine


The metabolism of Ranitidine can be decreased when combined with Darifenacin.

Ranolazine


The metabolism of Darifenacin can be decreased when combined with Ranolazine.

Remifentanil


The risk or severity of adverse effects can be increased when Darifenacin is combined with Remifentanil.

Remoxipride


The metabolism of Remoxipride can be decreased when combined with Darifenacin.

Ribociclib


The serum concentration of Darifenacin can be increased when it is combined with Ribociclib.

Rifabutin


The metabolism of Darifenacin can be increased when combined with Rifabutin.

Rifampin


The metabolism of Darifenacin can be increased when combined with Rifampicin.

Rifapentine


The metabolism of Darifenacin can be increased when combined with Rifapentine.

rimabotulinumtoxinB


Darifenacin may increase the anticholinergic activities of Botulinum Toxin Type B.

Risperidone


The metabolism of Risperidone can be decreased when combined with Darifenacin.

Ritonavir


The metabolism of Darifenacin can be decreased when combined with Ritonavir.

Rivastigmine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Rivastigmine.

Rolapitant


The metabolism of Darifenacin can be decreased when combined with Rolapitant.

Ropinirole


The metabolism of Darifenacin can be decreased when combined with Ropinirole.

Ropivacaine


The metabolism of Ropivacaine can be decreased when combined with Darifenacin.

Rotigotine


The metabolism of Rotigotine can be decreased when combined with Darifenacin.

Rucaparib


The metabolism of Rucaparib can be decreased when combined with Darifenacin.

Saquinavir


The metabolism of Darifenacin can be decreased when combined with Saquinavir.

Saquinavir Mesylate


The metabolism of Darifenacin can be decreased when combined with Saquinavir.

Sarilumab


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Sarilumab.

Scopolamine


The risk or severity of adverse effects can be increased when Scopolamine is combined with Darifenacin.

Scopolamine Hydrobromide


The risk or severity of adverse effects can be increased when Scopolamine is combined with Darifenacin.

Secretin


The therapeutic efficacy of Secretin can be decreased when used in combination with Darifenacin.

Sertindole


The metabolism of Sertindole can be decreased when combined with Darifenacin.

Sertraline


The metabolism of Sertraline can be decreased when combined with Darifenacin.

Sildenafil


The metabolism of Darifenacin can be decreased when combined with Sildenafil.

Siltuximab


The serum concentration of Darifenacin can be decreased when it is combined with Siltuximab.

Simeprevir


The serum concentration of Darifenacin can be increased when it is combined with Simeprevir.

Simvastatin


The metabolism of Simvastatin can be decreased when combined with Darifenacin.

Solifenacin


The risk or severity of adverse effects can be increased when Darifenacin is combined with Solifenacin.

ST. JOHN'S WORT EXTRACT


The serum concentration of Darifenacin can be decreased when it is combined with St. John's Wort.

Sufentanil


The risk or severity of adverse effects can be increased when Darifenacin is combined with Sufentanil.

Sulfisoxazole


The metabolism of Darifenacin can be decreased when combined with Sulfisoxazole.

Sulpiride


Darifenacin may increase the anticholinergic activities of Sulpiride.

Tacrine


The therapeutic efficacy of Darifenacin can be decreased when used in combination with Tacrine.

Tamoxifen


The serum concentration of the active metabolites of Tamoxifen can be reduced when Tamoxifen is used in combination with Darifenacin resulting in a loss in efficacy.

Tamsulosin


The metabolism of Tamsulosin can be decreased when combined with Darifenacin.

Tapentadol


The metabolism of Tapentadol can be decreased when combined with Darifenacin.

Tegaserod


The metabolism of Tegaserod can be decreased when combined with Darifenacin.

Telaprevir


The metabolism of Darifenacin can be decreased when combined with Telaprevir.

Telithromycin


The metabolism of Darifenacin can be decreased when combined with Telithromycin.

Terbinafine


The metabolism of Darifenacin can be decreased when combined with Terbinafine.

Terfenadine


The metabolism of Terfenadine can be decreased when combined with Darifenacin.

Tetrabenazine


The metabolism of Tetrabenazine can be decreased when combined with Darifenacin.

Tetrahydrocannabinol


Darifenacin may increase the tachycardic activities of Dronabinol.

Theophylline


The metabolism of Theophylline can be decreased when combined with Darifenacin.

Theophylline anhydrous


The metabolism of Theophylline can be decreased when combined with Darifenacin.

Thioridazine


The serum concentration of Thioridazine can be increased when it is combined with Darifenacin.

Ticlopidine


The metabolism of Darifenacin can be decreased when combined with Ticlopidine.

Timolol


The metabolism of Timolol can be decreased when combined with Darifenacin.

Timolol Anhydrous


The metabolism of Timolol can be decreased when combined with Darifenacin.

Tiotropium


Darifenacin may increase the anticholinergic activities of Tiotropium.

Tipranavir


The metabolism of Darifenacin can be decreased when combined with Tipranavir.

Tocilizumab


The serum concentration of Darifenacin can be decreased when it is combined with Tocilizumab.

Tolterodine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Tolterodine.

Topiramate


The risk or severity of adverse effects can be increased when Darifenacin is combined with Topiramate.

Trabectedin


The metabolism of Trabectedin can be decreased when combined with Darifenacin.

Tramadol


The therapeutic efficacy of Tramadol can be decreased when used in combination with Darifenacin.

Tranylcypromine


The metabolism of Darifenacin can be decreased when combined with Tranylcypromine.

Trazodone


The metabolism of Trazodone can be decreased when combined with Darifenacin.

Trichlormethiazide


The serum concentration of Trichlormethiazide can be increased when it is combined with Darifenacin.

Trihexyphenidyl


The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Darifenacin.

Trihexyphenidyl Hydrochloride


The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Darifenacin.

Trimethaphan


The risk or severity of adverse effects can be increased when Darifenacin is combined with Trimethaphan.

Trimipramine


The metabolism of Trimipramine can be decreased when combined with Darifenacin.

Tropicamide


The risk or severity of adverse effects can be increased when Tropicamide is combined with Darifenacin.

Trospium


The risk or severity of adverse effects can be increased when Trospium is combined with Darifenacin.

Tubocurarine


The risk or severity of adverse effects can be increased when Darifenacin is combined with Tubocurarine.

Umeclidinium


Darifenacin may increase the anticholinergic activities of Umeclidinium.

Valbenazine


The metabolism of Valbenazine can be decreased when combined with Darifenacin.

Vecuronium


The risk or severity of adverse effects can be increased when Darifenacin is combined with Vecuronium.

Vemurafenib


The serum concentration of Darifenacin can be decreased when it is combined with Vemurafenib.

Venlafaxine


The metabolism of Darifenacin can be decreased when combined with Venlafaxine.

Verapamil


The metabolism of Darifenacin can be decreased when combined with Verapamil.

Vilazodone


The metabolism of Vilazodone can be decreased when combined with Darifenacin.

Vinblastine


The metabolism of Vinblastine can be decreased when combined with Darifenacin.

Vinorelbine


The metabolism of Vinorelbine can be decreased when combined with Darifenacin.

Voriconazole


The metabolism of Darifenacin can be decreased when combined with Voriconazole.

Vortioxetine


The metabolism of Vortioxetine can be decreased when combined with Darifenacin.

Yohimbine


The metabolism of Yohimbine can be decreased when combined with Darifenacin.

Zalcitabine


The metabolism of Zalcitabine can be decreased when combined with Darifenacin.

Ziprasidone


The metabolism of Darifenacin can be decreased when combined with Ziprasidone.

Zolpidem


The metabolism of Zolpidem can be decreased when combined with Darifenacin.

Zuclopenthixol


The metabolism of Zuclopenthixol can be decreased when combined with Darifenacin.

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