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Q Fever (Query Fever) - Treatment

Medically Reviewed by dr. simi paknikar, MD on Jan 07, 2022


Treatment

Doxycycline is the most effective drug for Q Fever. The drug cotrimoxazole during pregnancy may cut down the risk of unfavorable outcomes of Q Fever.


Acute Q Fever can easily be treated with antibiotics. Doxycycline is the most efficient antimicrobial for Q Fever (a dose of 100 mg of doxycycline taken orally twice daily for 15–21 days). Alternative to Doxycycline are Quinolone antibiotics.

Chronic Q Fever endocarditis is much more difficult to treat. It requires a combination of drugs like: doxycycline in combination with quinolones, doxycycline in combination with hydroxychloroquine.

Surgery may be required in severe valve involvements. Patients with hepatitis may only improve when given a short course of glucocorticoids. The drug cotrimoxazole during the entire pregnancy may cut down the risk of unfavourable outcomes of Q Fever.

References:

  1. Cecil Medicine, 23rd ed.
  2. Harrison's PRINCIPLES OF INTERNAL MEDICINE, Seventeenth Edition.

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