Glibenclamide and Metformin - Drug Information
Generic Name : Glibenclamide and Metformin
Pronunciation : GLY-BEN-CLA-AMIDE +MetFORE-min
ICD Code : Y42.3 | Therapeutic Classification : Antidiabetics
Trade Name(s) :
India - Aviglen Fo, Aviglen-Mf, Benclamet, Benformin, Ben-Q-Met, Clamet, Clamet-C, Mide Plu, Combidos, Cuben-M, Daocon-M, Daonil-M, Diabetrol, Diatrac-M, Diolin-M, Dior Plus, Duotrol-Sr, Eumet-D, G-Formin, G-Formin-F, G-Formin-P, Glibact-M, Glibomet, Glibomet F, Glifil M F, Glinil-M, Glitrac-M, Glucomin-P, Gluconil-M, Glucored, Glucored F, Glucotrac, Glutowin F, Glycurb, Iscept. Iscept For, Iscpet 500, Iscept-L, Iscept-P, Melitus, Metclam, Metclam Fo, Metica G, Sugatrol, Sugatrol F, Sugnl-M, Triglycome.International - Glucovance.
Why is Glibenclamide and Metformin Prescribed? (Indications)
This medication contains sulfonylurea and biguanide antidiabetic combination, prescribed for type 2 diabetes.
When should Glibenclamide and Metformin not to be taken? (Contraindications)
Contraindicated in patients with severe kidney disease, chronic metabolic acidosis, diabetic ketoacidosis, with or without coma, and hypersensitivity.
What is the dosage of Glibenclamide and Metformin?
Adult: PO- Per tab contains glibenclamide 1.25 mg and metformin 250 mg. As initial therapy: Start with 1 tab 1-2 times/day. It may be increased if needed.
How should Glibenclamide and Metformin be taken?
It comes as a tablet to take by mouth, with food.
What are the warnings and precautions for Glibenclamide and Metformin?
* Caution should be exercised in patients with history of heart attack, heart, pituitary, or thyroid disease; adrenal insufficiency, stomach problem, infection, glucose-6-phosphate dehydrogenase (G6PD) deficiency, chronic metabolic acidosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Follow the diet and exercise program as directed by your physician.
* During hot season this medication may lead to dehydration; to avoid this problem drink adequate fluid.
* Monitor kidney and liver function, fasting blood glucose, hemoglobin A1c, and complete blood cell counts regularly while taking this medication.
* Extreme caution needed in children less than 6 years old.