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General Information on Glibenclamide and Metformin

Generic Name : Glibenclamide and Metformin

Pronunciation : GLY-BEN-CLA-AMIDE +MetFORE-min

Latest prescription information about Glibenclamide and Metformin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.3 | Therapeutic Classification : Antidiabetics

Trade Names/Brand Names of Glibenclamide and Metformin

India- Aviglen Fo, Aviglen-Mf, Benclamet, Benformin, Ben-Q-Met, Clamet, Clamet-C, Mide Plu, Combidos, Cuben-M, Daocon-M, Daonil-M, Diabetrol, Diatrac-M, Diolin-M, Dior Plus, Duotrol-Sr, Eumet-D, G-Formin, G-Formin-F, G-Formin-P, Glibact-M, Glibomet, Glibomet F, Glifil M F, Glinil-M, Glitrac-M, Glucomin-P, Gluconil-M, Glucored, Glucored F, Glucotrac, Glutowin F, Glycurb, Iscept. Iscept For, Iscpet 500, Iscept-L, Iscept-P, Melitus, Metclam, Metclam Fo, Metica G, Sugatrol, Sugatrol F, Sugnl-M, Triglycome.
International- Glucovance.

Why is Glibenclamide and Metformin Prescribed? (Indications)

This medication contains sulfonylurea and biguanide antidiabetic combination, prescribed for type 2 diabetes. 

When should Glibenclamide and Metformin not to be taken? (Contraindications)

Contraindicated in patients with severe kidney disease, chronic metabolic acidosis, diabetic ketoacidosis, with or without coma, and hypersensitivity.

What is the dosage of Glibenclamide and Metformin?

Adult: PO- Per tab contains glibenclamide 1.25 mg and metformin 250 mg. As initial therapy: Start with 1 tab 1-2 times/day. It may be increased if needed.

How should Glibenclamide and Metformin be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Glibenclamide and Metformin?

Caution should be exercised in patients with history of heart attack, heart, pituitary, or thyroid disease; adrenal insufficiency, stomach problem, infection, glucose-6-phosphate dehydrogenase (G6PD) deficiency, chronic metabolic acidosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Follow the diet and exercise program as directed by your physician.

During hot season this medication may lead to dehydration; to avoid this problem drink adequate fluid.

Monitor kidney and liver function, fasting blood glucose, hemoglobin A1c, and complete blood cell counts regularly while taking this medication.

Extreme caution needed in children less than 6 years old.

What are the side effects of Glibenclamide and Metformin?

Low blood sugar, upper respiratory tract infection, diarrhea, headache, nausea/vomiting, abdominal pain and dizziness.

What are the other precautions for Glibenclamide and Metformin?

Avoid excess dosage.

What are the storage conditions for Glibenclamide and Metformin?

Store it at room temperature and in an airtight container.


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Sibaprasad, India

Which drug is better - Daonil or Daonil M. I take metformimn separately, and good is not the result.

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