Edrophonium Injection - Drug Information
Generic Name : Edrophonium Injection
Pronunciation : ED roe FOE nee um
ICD Code : Y57.6 | Therapeutic Classification : Diagnostic Agents
Trade Name(s) :
International - Enlon, Tensilon, Reversol.
Why is Edrophonium Injection Prescribed? (Indications)
This medication is an acetylcholinesterase inhibitor, prescribed for diagnosis of myasthenia gravis. It prevents the breakdown of the neurotransmitter acetylcholine.
When should Edrophonium Injection not to be taken? (Contraindications)
Contraindicated in patients with intestinal, urinary obstruction; and hypersensitivity.
What is the dosage of Edrophonium Injection?
Adults- IV- The recommended dose is 1 mL (10 mg) and prepared with an intravenous needle, and 0.2 mL (2 mg) is injected intravenously within 15 to 30 seconds.
How should Edrophonium Injection be taken?
It comes as a solution for injection to be administered by a healthcare provider into the vein.
What are the warnings and precautions for Edrophonium Injection?
* Caution should be exercised in patients with history of asthma, heart rhythm disorder, any allergy, and during pregnancy and breastfeeding.What are the side effects of Edrophonium Injection?
Eye - Increased tears, pupillary constriction, spasm of accommodation, double visionand conjunctival hyperemia.Central Nervous System - Convulsions, speech disorder, voice disorder and difficulty in understanding.
Respiratory - Asthma, airway obstruction and central respiratory paralysis.
Heart - Abnormal heart rhythm, low blood pressure and increased salivation.
Gastrointestinal - Gastric and intestinal secretion, nausea, vomiting, increased peristalsis, diarrhea and abdominal cramps.
Musculoskeletal - Weakness and muscle twitch.
Miscellaneous - Increased urinary frequency and incontinence, increased sweating.