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Adenosine - Drug Information

Medically Checked by S. Hemamalini, B. Pharm on Nov 25, 2013


Generic Name : Adenosine
Pronunciation : a-DEN-oh-seen

ICD Code : Y52.2 | Therapeutic Classification : Antiarrhythmics

Trade Name(s) :

India - Adenoject (3 mg), Carnosine (30 mg), Carnosine, Adenoject, Adenoz, Adnet (3 mg), Adenocor, Adenoject (6mg), Tachyban, Adnet

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International - Adenocard, Adenoscan.



Why is Adenosine Prescribed? (Indications)

Adenosine is used as an antiarrhythmic agent prescribed to treat specific conditions of irregular heartbeat and also used while performing a stress test of the heart. It slows the electrical conduction in the heart.

When should Adenosine not to be taken? (Contraindications)

Contraindicated in patients with second-or third-degree AV block, slow heartbeat, and hypersensitivity.

What is the dosage of Adenosine?

Adult- IV- Initial dose: 6 mg given as a rapid intravenous bolus (administered over a 1-2 second period). Repeat Administration: If first dose does not work, 12 mg should be given as a rapid intravenous bolus. This 12 mg dose may be repeated a second time if required.
Child- Initial dose: Give 0.05 to 0.1 mg/kg as a rapid IV bolus. It may be increased up to 0.05 to 0.1 mg/kg if needed.

How should Adenosine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Adenosine?

* Caution should be exercised in patients with history of lung or breathing problems, gout, any allergy, who are taking other medications, elderly, during pregnancy and breast-feeding.
* It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid drinking large amount of caffeinated beverages.


What are the side effects of Adenosine?

Heart - Facial flushing, temporary rash on the chest, headache, sweating, palpitations, chest pain and low blood pressure.
Respiratory - Shortness of breath, chest pressure, fast breathing, coughing and head pressure.
Central Nervous System - Lightheadedness, dizziness, tingling in arms, numbness, apprehension, blurred vision, burning sensation, heaviness in arms, neck and back pain.
Gastrointestinal - Nausea, diaphoresis, metallic taste, tightness in throat and pressure in groin.

What are the other precautions for Adenosine?

* Monitor electrocardiogram (ECG) regularly while taking this medication.

What are the storage conditions for Adenosine?

Store it at controlled room temperature (15�-30�C), and in an airtight container.

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