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The Latest Gen About the Human Genome

by Medindia Content Team on  January 25, 2007 at 6:20 PM Research News   - G J E 4
The Latest Gen About the Human Genome
University of Alberta scientists seem to have unraveled a chemical correspondent of the human genome, in a breakthrough research. This finding promises to be a harbinger of novel ways of diagnosing diseases - by understanding the chemical composition of the human body. The project costing $7.5 million is funded by Genome Canada.
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In a maiden attempt at drafting the human 'metabolome', scientists identified and described 2,500 metabolites, 1,200 drugs and 3,500 food components, present in the human body.

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Project Leader Dr. David Wishart, professor of computing science and biological sciences at the University of Alberta, said, "Metabolites are the canaries of the genome. A single base change in our DNA can lead to a 100,000-times change in metabolite levels."

Basically metabolites are molecules which play a role in the processes that constitute the metabolism in a living being. When all the metabolic reactions form a network it is called a metabolome.

"Most medical tests today are based on measuring metabolites in blood or urine. Unfortunately, less than 1% of known metabolites are being used in routine clinical testing. If you can only see 1% of what's going on in the body, you're obviously going to miss a lot," Wishart added.



Source: Medindia
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