Stem cells in regeneration of breast tissue in Cancer patients

by Gayatri on  October 30, 2006 at 4:06 PM Genetics & Stem Cells News   - G J E 4
Stem cells in regeneration of breast tissue in Cancer patients
The American scientists have devised a technique that could put an end to reconstructive surgery for women recovering from breast cancer. It is expected that the stem cells derived the patient's own fat would help in regeneration of breast tissue.

In the preliminary 3-year program of animal research, the stem cells will be "seeded" on to scaffold structures that will serve as a platform around which the replacement tissue will grow.

Research leader Dr Peter Rubin, from the University of Pittsburgh School of Medicine, said: "The surgical options for breast reconstruction involve either the use of implants or a procedure whereby fat tissue taken from another part of the body is shaped into the form of a breast. Neither is ideal nor without risk.

"The use of adipose or fat-derived stem cells may represent a better solution for soft tissue reconstruction in breast cancer patients." The adaptability of fat-derived stem cells has been established by previous laboratory experiments.

These cells develop into cells characteristic of fat, bone, cartilage, nerve, muscle and blood vessels on exposure to certain chemical conditions. The team plans to combine fat-derived stem cells with microscopic beads with regenerative properties.

Initial tests reveal that the stem cells easily adhere to the beads and differentiate into mature fat cells. When these cells are in turn injected into the skin of the lab rats, mounds of tissue are formed by them.

"We need to demonstrate that fat-derived stem cells taken from a breast cancer patient behave no differently than those from other women," Dr Rubin said. "Moreover, our studies will seek to understand what effect, if any, these stem cells may have on cancer cells.

According to experts 200 million stem cells can be obtained from 454 gm of fat removed in a "tummy tuck" operation.

Source: Medindia

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions
please keep me posted on this procedure---
guest Thursday, June 14, 2007
I would love to know when this becomes available in the United States. I've been waiting for something like this!
guest Thursday, June 7, 2007
I have implants, but would like to be notified when this procedure becomes available. If I reach 65 before then, will medicare cover this? Could my implants be replaced even if they are still good? Thanks in advance for any info you can give me!
guest Monday, June 4, 2007
I will be starting reconstruction in October 2007, please let me know if this becomes available before then. Thank You.
guest Saturday, June 2, 2007
I am a survivor of 1 year. I would like to be notified when and if this would be available. I would also welcome any news on the cost and if insurance will cover it.Implants scare me! Surgery can be costly and painful.
guest Sunday, May 20, 2007
Sure hope this is available soon. I had implants and I'm about to have them replaced due to rupture.
guest Thursday, May 17, 2007
I wish this was ready today. I'm about to under go my third reconstruction surgery. It took a year to recover from the second one. There should be a better choice.
guest Sunday, April 15, 2007
How cool is that!! I hope this is successful and can be done years after the surgery!! There is always hope!
guest Friday, April 6, 2007
I hope this proves successful and will be approved because reconstruction(tram) is worse than mastectomy, chemotherapy and radiation combined. .
guest Sunday, March 11, 2007
guest Thursday, November 16, 2006

You May Also Like