login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
Research Shows How Eating Less can Make You Live Longer
"We're getting closer and closer to a good understanding of how caloric restriction works. This study is the first direct proof for a mechanism underlying the anti-aging effects we observe under caloric restriction," said Tomas A. Prolla at the University of Wisconsin-Madison.
The team found that an enzyme known as Sirt3 has anti-aging effects in mammals, according to John M. Denu of UW-Madison's Wisconsin Institute for Discovery.
Under reduced-calorie conditions, levels of Sirt3 amp up, altering metabolism and resulting in fewer free radicals produced by mitochondria - structures inside cells that produce energy and that are the sources of highly reactive forms of oxygen known as free radicals, which damage cells and promote the effects of aging.
The work involved a mouse model that exhibits age-related hearing loss.
"Hearing loss is associated with the loss of specific cell types in the cochlea. And hearing loss is prevented through caloric restriction," said Prolla.
The team showed that elevated levels of Sirt3 protect cells from cell stress and death caused by free radicals. Knowing the molecular basis of how the sirtuin enzymes work may ultimately lead to the rational development of drugs that activate the pathways of enzymes like Sirt3 to slow down the process of aging.
The study is published in Cell.
Source-ANI
|
|
More News on: Life Span or Death Clock, Tips to Live Longer
 Comment & Contribute
|
- Health News Index
- News Quick Links
| News Categories: |
| » | Schizophrenia Drug Differentiates Cancer Stem Cells into Less Threatening Cells |
| » | Docs Who Seldom Meet Drug Reps Continue to Prescribe Drugs With FDA “Black Box” Warnings |
| » | Revision in Quality Standards for Heparin |
| » | Acne Drug Users At High Risk of Developing Eye Infections |
| » | Patients Who Take Antidepressants When in ICU More Likely to Die |
| More Drug News | |
|
