Custom Search

Register
Sign In
Sign In Using Facebook

Fatal Forms of Malaria Identified by Protein Biomarkers

by Hannah Punitha on  December 09, 2008 at 1:02 PM Tropical Disease News
  •   Print
  •   Share
  •   Comments
  •  Text 
 Fatal Forms of Malaria Identified by Protein Biomarkers
Canadian researchers have identified protein biomarkers that could facilitate easy diagnosis of two severe and debilitating forms of malaria.


With the findings, scientists have shed new light on the development two crippling malaria variations - one that develops in the placenta of pregnant women affecting countless unborn children, the other, cerebral malaria, that develops in the brain's blood vessels - malaria's most deadly form.

Since ages malaria has notoriously stalked pregnant women, said Tropical disease specialists affiliated with Toronto's McLaughlin-Rotman Centre for Global Health (MRC).

A decade ago, researchers showed malaria parasites could accumulate in the newly created placenta. But Dr. Kevin Kain, Director of the Sandra A. Rotman Laboratories at the MRC, said that it's still unclear how parasites hiding in the placenta actually result in placental and foetal injury.

And in the new research, the scientists claim to have unravelled part of this mystery, by finding that women with placental malaria carry a biomarker in their blood - a protein called C5a, which is an important part of the body's innate defence against infections but one that needs to be carefully controlled.

At the time of over-activation by malaria infection, C5a appears leads to an excessive inflammatory response and disrupts normal blood vessel growth in the placenta, raising the risk of spontaneous abortions or low birth weight infants.

The scientists conducted tests on pregnant women in Kenya, and found that those with placental malaria had elevated levels of C5a in their blood compared to expectant mothers without the disease.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
Comment & Contribute
Be the first to comment!
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  

X
  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Oncology - Focus on Cancer Prevention
News Archive
Date :
Category :
Keyword :
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
Malaria
Complete Medindia Resources
News Categories:  
Senior Health Center

Tropical Disease Related News

» 'Test and Treat' Model Provides New Tactic for Malaria Eradication » Research on Vitamins Can Craft Novel Drugs to Encounter Malaria, Claims Southampton Varsity
» Vitamin Biosynthesis Discovery Might Lead to Fresh Anti-Malaria Drug » Malaria's Genetic Secrets Could be Unravelled by Latest Technique
» UN Reports Spike in Cholera Cases in DR Congo » Mass Vaccination for Low Diffusion Areas Intimated by New Model for Likely Malaria Vaccination
» Disparities in Wealthy States Mounts, Maladies Sink: WHO » Cardinal Protein the Survival of Malaria Parasite Detected
Read More >>