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How to Take Amifostine and it's Dose


This medication available in the form of injection, administered by the healthcare providers.

Dosage & When it is to be taken

As a cell protective agent in chemotherapy and radiation.
Adult: Initially, 910 mg/m2 BSA once daily, as an infusion given over 15 minutes, 30 minutes before start of chemotherapy. May reduce to 740 mg/m2 if patient is unable to tolerate the full dose.
For patients receiving cisplatin- <100 mg/m2, a dose of 740 mg/m2 may be given to reduce renal toxicity.
Prophylaxis of dry mouth in patients undergoing radiotherapy for head and neck cancer- Adult: 200 mg/m2 BSA once daily, as an infusion given over 3 minutes, beginning 15-30 minutes before radiotherapy.

When it is not to be taken (Contraindications)

Contraindicated in patients with low BP, dehydration, patients with kidney or liver disease, children and elderly >70 years, and hypersensitivity.

Drug Name : Amifostine

This medication is a cytoprotective agent, prescribed for preventing kidney damage due to chemotherapy and reducing the mouth dryness due to radiation therapy.


Trade Names/Brand Names of Amifostine

India :


International :


Ethyol
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