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Perflutren Protein-Type A Microspheres

Updated on : August - 2012
Latest prescription information about Perflutren Protein-Type A Microspheres. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Perflutren Protein-Type A Microspheres
Pronunciation : per-FLOO-tren
Therapeutic Classification : Contrast Medium
Trade Name(s): 
International- Optison.
Why it is prescribed (Indications) : 
This medication is a contrast agent, used to diagnose heart diseases during certain medical tests (e.g., echocardiograms). It helps in clear visualization of heart.
When it is not to be taken (Contraindications): Contraindicated in patients with any allergy.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
The recommended dose is 0.5 mL injected into a peripheral vein.
How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider into the peripheral vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history lung disease, or heart disease, who are taking other medications, any allergy, during pregnancy and breastfeeding.
* It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
Patient may develop with increased risk of fatal cardiac or respiratory arrest; if it is so consult with your doctor immediately.
Side Effects : 
Body as a Whole - Headache, warm sensation, flushing, chills, fever, flu-like Symptoms, uneasiness, weakness, fatigue, dizziness.
Heart - Chest pain.
Gastrointestinal - Nausea and/or vomiting.
Respiratory - Difficulty in breathing.
Skin - Injection site discomfort, redness.
ENT - Altered taste.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2°-8°C).
♦ Safety Labeling Changes Approved By FDA

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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