The quick and easy procedure saw doctors take bone marrow from the patients' hips before injecting them directly into the heart to strengthen the muscle, the Daily Express reported.
Heart pumping function improved within six months for every patient given the ground-breaking treatment. They also enjoyed improved fitness and could walk longer distances.
The trial offers new hope to the tens of thousands of people struck down by heart failure each year in the UK and could transform the lives of millions suffering the after-effects of a heart attack.
Lead researcher Dr Andre Terzic said: "I think it's an exciting time where regenerative medicine is no longer science fiction. This study is providing clinical evidence for a new approach in cardiovascular regenerative medicine."
The research is published online in the Journal of the American College of Cardiology.