Premature Ageing in Kids Could Be Tackled by Two Drugs

Two common drugs used to reduce cholesterol, and a drug used to curb osteoporosis can offer a treatment option for premature ageing in kids, a new study has found.

Progeria is a rare genetic disease that causes premature ageing and is usually fatal before puberty.

Cholesterol - Lipoproteins - Functions - Normal Blood Cholesterol Levels - Causes - Treatment - FAQs
Cholesterol is produced by the body (liver) and is essential for normal body functioning.

Premature ageing is caused by gene mutations that affects the production of a protein called prelamin A, critical for the disease.

The protein then ties to molecular fragments in the body called farnesyls, which in turn bind to the nuclear membrane, leading to protein accumulation, reports New Scinetist.

In the study conducted over mice with progeria, lead researcher Carlos Lopez-Otin of the University of Oviedo, Spain found that combination of two drugs reduced ageing symptoms and increased survival rates.

High Cholesterol | Hypercholesterolemia - Causes, Symptoms, Diagnosis & Treatment
High cholesterol level in blood are a risk for heart disease and stroke. They get deposited in the wall of the arteries and clog the circulation posing a threat to life.

The researchers are now seeking permission to conduct human trails to understand whether statins and bisphosphonates would help them.

The study appears in Nature Medicine.

Fish Oil and Yeast Rice Effectively Control Bad Cholesterol: Study
Researchers from University of Pennsylvania Health System have revealed that fish oil and yeast rice supplements can effectively lower bad cholesterol levels, thus proving a better

Source-ANI
RAS/L

'Caveman Diet' Lowers Heart Attack, Stroke Risk
Eating the basic caveman diet of berries, nuts, lean meat and fish significantly lowers the chance of suffering a heart attack or stroke, says a new study.