Cell free nucleic acids (cfNA) are genetic sequences. They are not attached to cells. They can be found circulating in the blood. These acids can be used to detect mutations in genetic sequences and can thereby be used as a 'liquid biopsy' tool for diagnosis of several types of cancer.
Scientists from University of Toronto have developed a simple method of analyzing the amount of mutated cfNA present in patient blood.
Breast Cancer Screening using Mammogram
Breast cancer if detected early can be completely cured. Mammography is used to screen women for breast cancer.
Advertisement
The study details the fabrication of an electrochemical clamp assay targeted towards detecting mutations in the KRAS gene, which causes lung, colorectal and ovarian cancer. The assay works by mixing in clamps that are specific for all other mutations except the mutation of interest, leading to a solution that has only the target mutation free of clamps.
This solution is then applied to a sensor, where the target mutation binds, and is detected with the help of an electrochemical sensor. The other mutations which have been clamped are not able to bind to the sensor and are finally washed away.
![Breast Cancer during Pregnancy]( "Breast Cancer during Pregnancy")
Management of breast cancer during pregnancy or pregnancy associated breast cancer requires special consideration to avoid harm to the fetus.
The electrochemical clamp assay requires much less volumes of serum, and can be performed on undiluted serum, which leads to simplicity in workflow and minimized sample loss. Also, the test can produce results in as little as 5 minutes, and can cut down on significant costs involved in cancer diagnosis.
Source: Medindia
Breast Cancer during Pregnancy
Management of breast cancer during pregnancy or pregnancy associated breast cancer requires special consideration to avoid harm to the fetus.
Advertisement
The electrochemical clamp assay requires much less volumes of serum, and can be performed on undiluted serum, which leads to simplicity in workflow and minimized sample loss. Also, the test can produce results in as little as 5 minutes, and can cut down on significant costs involved in cancer diagnosis.
Source: Medindia
Laryngeal Cancer
Laryngeal cancer is also called cancer of the larynx or throat cancer or laryngeal carcinoma. It usually affects men over the age of 55 years.
Advertisement
 Maxillary Sinus CancerCancers of paranasal sinuses are rare but if they arise, the most common sites affected are the maxillary sinuses. | Advertisement
|
Advertisement
Recommended Reading
Latest Cancer News
A new study assessed the association of cigarette smoking and vaping on cancer-related symptom burden (fatigue, pain, emotional problems) and quality of life.
Scientists are making strides in personalized breast cancer therapy by developing a highly accurate molecular classifier test for breast cancer patients.
Experts suggest high-income countries implement a comprehensive risk-based approach for prostate-specific antigen (PSA) testing to reduce overdiagnosis and overtreatment.
New study identifies the role of metabolic comorbidities such as obesity in contributing to the immunogenicity of oral cancer through the immune pathway STING-IFN-I.
Recent clinical trial results have shown that reducing the dose and duration of radiotherapy treatments for anal cancer may result in fewer side effects.