About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Neurological Brain Markers Help Detect Psychotic Disorders Risk

by Colleen Fleiss on August 29, 2019 at 5:25 AM
Font : A-A+

Neurological Brain Markers Help Detect Psychotic Disorders Risk

Neurological markers present in human brain were found to detect people at-risk for developing psychotic disorders and to understand when this risk has been successfully treated, said University of Missouri researchers. People who may hear and see things that are not there could have symptoms of psychosis, better known as psychotic disorders.

"Psychotic disorders like schizophrenia are often lifelong and disabling for individuals," said John Kerns, professor of psychology in the MU College of Arts and Science. "These disorders have major public health and societal costs greater than cancer. A major goal of our current research is to understand the nature of psychosis risk so we can prevent years of suffering."

Advertisement


Researchers said psychotic disorders are associated with increased levels of dopamine -- a chemical released by nerve cells -- in a subregion of the brain called the striatum. This area is wired to process positive versus negative feedback for learning, often resulting in a person's thoughts and actions based on what they've experienced in the past. Therefore, researchers suggest that psychotic disorders involve a faulty feedback in learning that then drives a person's faulty beliefs and perceptions. However, measuring levels of dopamine in people is costly, invasive and not feasible in everyday clinical practice.

"This dysfunction is most evident when performing tasks where people need to learn from positive and negative feedback," Kerns said. "For instance, we have found that the risk for psychotic disorders involves increased activation in the striatum for positive feedback, and negative feedback involves decreased activation in the same subregion of the brain."
Advertisement

Researchers believe this pattern of activation could explain symptoms of psychotic disorders. For example, activation resulting from increased positive feedback could make a person's assumption seem truer than it really is, meanwhile activation from decreased negative feedback could make someone less likely to discard negative ideas. The team will conduct future research to examine how well an MRI can predict the risk of psychotic disorders and whether prevention treatments can 'normalize' MRI scans. They hope that their research will help prevent psychotic disorders, improve the lives of millions of people and greatly reduce public health costs.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Goji Berries May Protect Against Age-Related Vision Loss
Tapping — A Proven Self-Applied Stress Intervention
Black Pepper as Preventive Measure Against Omicron
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Parkinsons Disease Surgical Treatment Brain Brain Facts Ataxia Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) 

Recommended Reading
Schizophrenia
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social ......
Quiz on Schizophrenia
Schizophrenia is a mental disorder that affects young adults; nearly 7% of the adult population ......
Brain Depression - Animation
Interactive section of Medindia provides information about chemistry of Brain depression...
Novel Technology-based Tools Improve Schizophrenia Risk Prediction
New digital tools and technology can help predict earlier signs of schizophrenia by identifying the ...
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)