The study found that post-menopausal women who received estrogen-only medication reported markedly lower frequency of joint pain compared to women who received a placebo.
"These findings suggest estrogen may provide modest but sustained relief for post-menopausal women who suffer from joint pain. Women should consult their physicians and balance the potential therapeutic value of estrogen against the available information on risks and benefits of menopausal hormone therapy, including the admonition to use the lowest dose for the shortest duration. Recent follow-up studies from the WHI found the benefits of taking estrogen-only medication could outweigh the risks for about five years."
In teenage girls with anorexia nervosa, the low bone density is improved by estrogen therapy. Estrogen is given as a patch or as a low oral dose.(close to the form or amount of estrogen the body makes naturally).