Scientists at an American research institute claim that they have been successful in reversing the impact of a mutation in the gene coding the protein dystrophin, known to be associated with muscular dystrophy.
Dr. Lorenzo Puri and his colleagues at the Burnham Institute for Medical Research say that their study showed that the dystrophin mutation causes an increase in the amount of the histone deacetylase enzyme, HDAC2, which in turn alters the gene expression profile in the diseased muscle cells compared to normal muscle cells.
Muscular Dystrophy / Duchenne Muscular Dystrophy - Overview
Overview about muscular dystrophy, a muscle disease characterized by muscle weakness and muscle wasting.
Overview about muscular dystrophy, a muscle disease characterized by muscle weakness and muscle wasting.
They claim that their breakthrough work might lead to novel therapies for muscular dystrophy.
Source-ANI
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Undervalued Protein Found To Improve Severe Muscular Dystrophy
Rockefeller University scientists say that an overlooked and undervalued protein, sarcospan, may ameliorate the most severe form of muscular dystrophy if added to muscle cells.
Rockefeller University scientists say that an overlooked and undervalued protein, sarcospan, may ameliorate the most severe form of muscular dystrophy if added to muscle cells.
