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Can COVID-19 Booster Dose Improve Antibodies?

by Angela Mohan on Jun 23 2022 4:41 PM
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Can COVID-19 Booster Dose Improve Antibodies?
High levels of Omicron-specific antibodies can be produced in nursing home residents and their caregivers with a third dose or booster dose of the COVID-19 vaccine.
The findings were published in the journal eBioMedicine.

Neutralizing antibodies are protective proteins produced by the immune system in response to vaccination and can be analyzed to determine the length of time it takes for immunity to diminish.

Effectiveness of Booster Dose of COVID-19 Vaccine

Omicron antibodies reached detectable levels in 86% of nursing home residents and 93% of healthcare workers after receiving the booster shot, compared to just 28% of nursing home residents and healthcare workers after the initial two-dose COVID-19 vaccine series. This high neutralization level occurred two weeks after the booster.

One in eight nursing home residents and one in nine staff members have not been fully vaccinated, according to the AARP (formerly called the American Association of Retired Persons).

David Canaday, lead study author said that the results highlight the importance of booster dose of COVID-19 vaccination not only for nursing home residents, but also for the general population.

Frail, older adults with similar clinical and functional limitations would benefit immensely from the booster dose.

Healthcare workers achieved a significant elevation in antibody levels after receiving the booster dose. Many of these workers are healthy, middle-aged adults similar to the general population.

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Previous study showed that nursing home residents and healthcare workers lose more than 80% of their COVID-19 immunity six months after the initial vaccine series. Those results were presented to the CDC and published last fall.

The CDC recommends a first booster dose for children ages 5 and older after completing their primary COVID-19 series. A second booster shot is recommended for people at least 50 years old and for those at least age 12 who are moderately or severely immunocompromised.

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Source: Medindia


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