Postpartum depression is a kind of a clinical depression that occurs after childbirth. Preventive treatment with antidepressants may not necessarily protect non-depressed, pregnant women with histories of major depressive disorders, finds a recent study from the UCLA research.
Asking questions about their daily activities, especially in terms of work may be an effective screening tool that helps doctors to identify women who are at a risk of depression after childbirth.
BACKGROUND: Twenty percent of adult women will experience an episode of major depressive disorder at some point in their lives. Women with a history of depression are particularly vulnerable to depression after they give birth. UCLA researchers recognized that there is a lack of data on predictors of postpartum depression in women with previous histories of depression but who don't suffer from it during pregnancy.
Scientists enrolled participants in the study between 12 and 36 weeks gestation. A study psychiatrist assessed each woman's mood and psychotropic medication at least twice, once within 60 days before their babies' due dates and again within 60 days after delivery. The researchers used structured, clinical interviews including questions about work activities and difficulties, insomnia and suicidal thoughts.
IMPACT: In contrast to previous studies, UCLA researchers found that among women with prior histories of major depressive disorder but who were not depressed when they become pregnant, only 11 percent developed postpartum depression. That figure is significantly lower than the 25 to 40 percent depression occurrence found in other studies.
Additionally, researchers also found that prescribing preventive antidepressants for this group of women did not affect the risk for developing postpartum depression, and also that a better predictor of postpartum depression were clinical interviews with the women about work activities, insomnia and suicidality.
The findings suggest that structured interviews about difficulties at work could alert doctors to patients at risk of postpartum depression who might benefit from being referred to a psychiatrist for monitoring after they give birth.