Bivalirudin Used as an Anticoagulant in Interventional Cardiovascular Procedures

New study highlights the use of bivalirudin for anticoagulation in interventional cardiovascular procedures. The findings of the study are published in the journal Cardiovascular Innovations and Applications.

Anticoagulation is //imperative to reduce the incidence of thrombotic complications in patients undergoing percutaneous interventional cardiovascular procedures; however, this is at the expense of increased risk of bleeding. The optimal anticoagulation strategy for these procedures remains unclear.

Bivalirudin Drug Effective in Heart Attack Treatment
Administration of an anticoagulant medication bivalirudin proves to improve the survival rate in heart attack patients when compared to heparin and a glycoprotein IIb/ IIIa inhibitor.

‘Clinical use of bivalirudin as an anticoagulant may help treat patients undergoing percutaneous coronary intervention and transcatheter aortic valve replacement procedures.’

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Unfractionated heparin is the most commonly used anticoagulant during interventional procedures, but has several limitations, such as a relatively high incidence of bleeding events, the occurrence of heparin-induced thrombocytopenia, and a paradoxical thrombotic effect.

Contemporary studies have demonstrated that bivalirudin decreases the occurrence of bleeding complications, but potentially increases the risk of acute stent thrombosis.

The authors discuss the pharmacology of bivalirudin and its current clinical application in patients undergoing percutaneous coronary intervention and transcatheter aortic valve replacement procedures.

Research Sheds Light on Use of Bivalirudin Versus Heparin in Patients Planned for Coronary Stenting
Among patients undergoing coronary stenting for ischemic heart disease, bivalirudin and heparin are two anticoagulant options.

Source-Eurekalert

Pre-Hospital Administration of Bivalirudin More Effective Than Heparin in Reducing Mortality Risk Among Heart Attack Patients
Blood thinner bivalirudin is more effective than heparin with optional use of glycoprotein IIb/IIIa inhibitors in reducing risk of death and major bleeding complications in patients with heart attack.

Coronary Heart Disease - Causes, Symptoms, Risk Factors, Diagnosis, Tretment
In coronary heart disease, blood is unable to flow through blocked arteries. The main symptom is chest pain or angina. Treatment is with medications or surgery.