About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

An ‘Off Switch’ For Cancer Could Be Identified Very Soon

by Aruna on August 17, 2009 at 11:01 AM
Font : A-A+

An ‘Off Switch’ For Cancer Could Be Identified Very Soon

Michigan State University scientists have identified a new mechanism that will help them move closer to finding an "off switch" for cancer.

Cancer cells divide uncontrollably and can move from one part of the body to another. They undergo dramatic shifts in shape when they do so.

Advertisement

Aaron DeWard, an MSU cell and molecular biology doctoral candidate, and colleagues are trying to figure out how certain proteins trigger cell movement and division and how cancer hijacks the system to create genomic instability.

The researchers studied proteins called formins that help determine the shape of a cell during division and movement.

They identified a new mechanism for regulation of formins during cell division.
Advertisement

"One of the cool things about these proteins is that they're tightly regulated - they will only do their jobs when they're told to do so," DeWard said, describing formins as the workers that put together the pieces that shape a cell.

"A lot of work has been done on how to get these proteins to work, but not when to stop working.

"We identified the way in which these proteins get flagged for destruction. This mechanism is pretty common for a lot of proteins, but had never been shown for this family of proteins before, and no one really knew how to shut them off completely," he added.

"Aaron's observation gives us a handle on the molecular machinery controlling cell division," said VARI senior scientific investigator Art Alberts.

"Our goal now is to exploit this information in the development of strategies to specifically stop the process of uncontrolled cell division that characterizes cancer," he added.

The study is published in the Journal of Biological Chemistry.

Source: ANI
ARU
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Cancer Facts Cancer Tattoos A Body Art Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant Immune Checkpoint Inhibitors for Cancer Treatment Non-Communicable Diseases 

Recommended Reading
Anti-psychotic Drugs Can Fight Major Cancers too
Anti-psychotic drugs can fight major cancers too, Australian research seems to show....
Researchers Strive for Therapies to Prevent Uncontrolled Cell Division in Cancer
Researchers from the Ludwig Institute for Cancer Research at the University of California, San ......
Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most...
Health Benefits of Dandelion Plant
What is dandelion? Dandelion greens are nutrition powerhouses with a wide range of health benefits. ...
Immune Checkpoint Inhibitors for Cancer Treatment
Immune checkpoint inhibitors are promising drugs to treat a variety of cancers and the FDA has appro...
Non-Communicable Diseases
Non-Communicable Diseases (NCDs) are a group of chronic non-infectious diseases which include Cardio...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use