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Mother's BPA Exposure Increases Asthma Risk in Kids

by Rajshri on Feb 5 2010 5:28 PM

Researchers at the University of Texas Medical Branch at Galveston have revealed that a mother's exposure to bisphenol A, may increase the risk of asthma in her kids.

In a mice study, the researchers found that offspring of female mice exposed to BPA had high risk of asthma compared to offspring of mice that had been protected from BPA. "We gave BPA in drinking water starting a week before pregnancy, at levels calculated to produce a body concentration that was the same as that in a human mother, and continued on through the pregnancy and lactation periods," said lead author Terumi Midoro-Horiuti.

The researchers gave an allergy-provoking ovalbumin injection to the mice four days after birth and continued to expose them to the allergen, which is mainly found in egg white. They then measured antibodies against ovalbumin and quantities of inflammatory white blood cells in the lungs of the mice.

"All four of our indicators of asthma response showed up in the BPA group, much more so than in the pups of the nonexposed mice," said co-researcher Randall Goldblum




Source-Medindia
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