Indications : This test is used to detect hemolytic disorders associated with Heinz body formation.
Physiology : Heinz bodies are intra-erythrocytic insoluble inclusions of oxidatively denatured hemoglobin. They reflect the presence of metabolic derangement of or abnormality in the secondary structure of hemoglobin.
Normal Range : No Heinz bodies identified.
Interpretation : Heinz bodies are present during G-6-PD deficiency, Heinz body hemolytic anemia (HBHA). Oxidative denaturation of hemoglobin leads to formation of Heinz bodies.
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