Grading & Staging of Non Hodgkins Lymphoma (NHL)
Grading & Staging of Non Hodgkins Lymphoma (NHL)
Grading describes the indolent or aggressive nature of the tumor. NHL may be graded as low-, intermediate-, or high-grade. Staging refers to the extent of progress the disease has made.There are individualistic deviations in what these descriptions mean for successful treatment. For instance, it cannot be deduced that a stage IV, high-grade patient has fewer hopes for remission than a stage IV, low-grade patient.
Staging broadly depends on the regions and number of lymph n odes involved and also if one has certain associated symptoms or not.
If there are no associated symptoms 'a' is added to the stage e.g Stage IIIa and if there are certain symptoms like fever, loss of weight etc., the letter 'b' is added.
Staging of NHL according to the Ann Arbor staging system is as follows:
| Stage | Organs /Regions affected |
| I | Single Lymph Node; sometimes one extra nodal site may be involved (IE) |
| II | Two or more lymph nodes involved; sometimes one extra nodal site may be involved (IIE) |
| III | Lymph node on either sides of the diaphragm are involved. Involvement of an extra nodal organ such as the liver or spleen (IIIS) or both (IIIS+E) is observed |
| IV | Disease widely spread with involvement of different regions/organs |
A - no associated symptoms with the disease and the patient may feel well
B - Assocaited symptoms like fever, loss of weight, sweating in evenings or night, loss of appetite
Non-Hodgkins Lymphoma - Reference:
- J. Occup. Environ. Med2002 May; 44(5): 469-74
"Occupation and risk of non-Hodgkin's lymphoma and chronic lymphocytic leukemia".
Zheng T, Blair A, Zhang Y, Weisenburger DD, Zahm SH.
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APA
Dr. Reeja Tharu. (2020, May 21). Grading & Staging of Non Hodgkins Lymphoma (NHL). Medindia. Retrieved on Apr 29, 2024 from https://www.medindia.net/health/conditions/non-hodgkin-lymphoma-staging.htm.
MLA
Dr. Reeja Tharu. "Grading & Staging of Non Hodgkins Lymphoma (NHL)". Medindia. Apr 29, 2024. <https://www.medindia.net/health/conditions/non-hodgkin-lymphoma-staging.htm>.
Chicago
Dr. Reeja Tharu. "Grading & Staging of Non Hodgkins Lymphoma (NHL)". Medindia. https://www.medindia.net/health/conditions/non-hodgkin-lymphoma-staging.htm. (accessed Apr 29, 2024).
Harvard
Dr. Reeja Tharu. 2020. Grading & Staging of Non Hodgkins Lymphoma (NHL). Medindia, viewed Apr 29, 2024, https://www.medindia.net/health/conditions/non-hodgkin-lymphoma-staging.htm.