Intermittent Fasting and Caloric Restriction Can Slow Brain Aging

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Highlights:

• OXR1 gene identified as a guardian of brain health and longevity
• Cellular mechanism showcases how dietary restriction slows aging
• Intermittent fasting emerges as a powerful strategy for neuroprotection and increased lifespan

In a study conducted by scientists at the Buck Institute for Research on Aging in California, the key role of a gene called OXR1 has been described, shedding light on the mechanisms behind the lifespan extension associated with dietary restriction and its crucial impact on healthy brain aging. The researchers suggest that adopting diet patterns such as intermittent fasting or calorie restriction may be instrumental in slowing down brain aging and increasing lifespan (1^✔).

The OXR1 Gene: Guardian of Brain Resilience

Published in the journal Nature Communications, the study emphasizes the significance of the OXR1 gene as a critical factor in promoting brain resilience against aging and neurological diseases. According to Kenneth Wilson, a postdoctoral student at the Institute, the prevailing notion often associates dietary restrictions with effects on the digestive tract or fat accumulation, overlooking its profound impact on the brain. "As it turns out, this is a gene that is important in the brain," Wilson notes.

Intermittent Fasting: A Pathway to a Healthier, Longer Life

The research team delves into a detailed cellular mechanism that elucidates how dietary restriction can effectively delay aging and impede the progression of neurodegenerative diseases. Employing fruit flies and human cells for their study, the researchers identify potential therapeutic targets that could be leveraged to combat aging and age-related neurodegenerative disorders.

‘Did you know? Intermittent fasting enhances OXR1 gene expression, safeguarding the brain from aging. #fasting #brain #medindia’

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